research Inherited Disorders of the Hair
The document explains the genetic causes and characteristics of inherited hair disorders.
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research The Genetics of Human Skin Disease
Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
research A Spontaneous Deletion Within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype
A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.
research Targeting the Stem Cell Niche: Role of Collagen XVII in Skin Aging and Wound Repair
Collagen XVII is important for skin aging and wound healing.
research Hair Graying and Loss Induced by Imatinib Mesylate
A woman's hair turned gray and fell out after starting a cancer drug called imatinib mesylate.
research Mapping the Molecular and Structural Specialization of the Skin Basement Membrane for Inter-Tissue Interactions
The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
research mTORC1 Activity Controls Human Scalp Hair Follicle Pigmentation and Growth
mTORC1 activity is important for hair growth and color, and targeting it could help treat hair loss and greying.
research Hair Growth Properties of Cinchona Succirubra Extract, Leontopodium Alpinum Extract, and Manganese PCA in Human Hair Follicle Dermal Papilla Cells
The ingredients could help prevent hair loss by promoting hair growth and increasing VEGF secretion.
research Structure and Function of the Skin
The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
research Evaluation of Anti-Hair Loss Shampoo Through In Vitro Activity in Human Hair Follicle Dermal Papilla Cells and Sensorial Study
The anti-hair loss shampoo effectively promotes hair growth and improves hair quality.
research Epithelial Stem Cells: Turning Over New Leaves
Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
research Mapping the Molecular and Structural Specialization of the Skin Basement Membrane for Inter-Tissue Interactions
The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
research The Significance of Scalp Involvement in Pemphigus: A Literature Review
Scalp involvement is common in pemphigus and can lead to hair loss, with the severity of scalp lesions linked to overall disease severity.
research Scalp Involvement in Pemphigus: A Prognostic Marker
Scalp involvement in pemphigus means the disease is more severe and harder to treat.
research Recreation of a Hair Follicle Regenerative Microenvironment: Successes and Pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research Localized Hypotrichosis Type 1 Due to Intragenic Deletion of Exons 5-8 in Desmoglein Gene in a Neonate from Indian Family
A baby from an Indian family had a rare genetic disorder causing no scalp or body hair due to a specific gene deletion.
research Identification of a Novel Homozygous LAMB3 Mutation in a Chinese Male With Junctional Epidermolysis Bullosa and Severe Urethra Stenosis: A Case Report
A Chinese male with a new genetic mutation has a skin condition and severe urinary issues, with treatments having mixed success.
research Independent DSG4 Frameshift Variants in Cats with Hair Shaft Dystrophy
Cats with abnormal hair had DSG4 gene changes causing hair problems.
research Geriatric Dermatology: Overview
Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.
research The Role of Integrin AlphaVbeta6 in Impaired Wound Healing and Hair Follicle Regeneration
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
research Signaling Involved in Hair Follicle Morphogenesis and Development
The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
research Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition
Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
research Variant PADI3 in Central Centrifugal Cicatricial Alopecia
Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.
research Biology and Genetics of Hair
The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
research Learning From Nudity: Lessons From The Nude Phenotype
The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
research Mutations in the Desmoglein 4 Gene Are Associated with Monilethrix-Like Congenital Hypotrichosis
Mutations in the DSG4 gene can cause a rare hair disorder similar to monilethrix.
research Next Generation Human Skin Constructs as Advanced Tools for Drug Development
Advanced human skin models improve drug development and could replace animal testing.
research Mechanical Forces in Skin Disorders
Skin problems can be caused or worsened by physical forces and pressure on the skin.
research Bi-Allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex
Mutations in the LSS gene cause a rare type of hereditary hair loss.
research Congenital Hair Loss Disorders: Rare, But Not Too Rare
Some hair loss disorders are caused by genetic mutations affecting hair growth.