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Targeted cancer therapies often cause serious skin problems that need careful management.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Follicular Unit Extraction (FUE) is a less invasive hair transplant method with minimal scarring, suitable for about 60% of patients, especially those needing fewer grafts and quicker recovery.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Understanding hair follicle anatomy helps diagnose hair disorders.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.

Psoriasis skin changes are complex and might need several biopsies for a clear diagnosis.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Fullerenes show potential in skin care but need more safety research.

Voriconazole can cause serious side effects, especially in long-term use.

New antifungal treatments for a children's scalp infection are effective and safe, but it's not decided if they will become the preferred option over the old treatment.

Kawasaki Disease is rare and often missed in adults, who show different symptoms than children, and may benefit from early treatment.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

The Lexington LaserComb helped regrow hair in mice with a condition similar to human hair loss.