September 2024 in “Health Problems of Civilization” This study describes the efficacy of oral isotretinoin in treating severe, hormonal, and treatment-resistant acne, noting significant side effects that depend on dose and duration, including teratogenic risks and common issues like skin dryness, while underscoring the importance of systematic monitoring to mitigate adverse effects.
June 2022 in “Research Square (Research Square)” In this study, higher DHA/omega-6 fatty acid ratios were linked to increased social impairment in individuals with autism, alongside lower antioxidant enzyme levels and higher markers of lipid peroxidation.
August 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This review discusses the effects of mineralocorticoid receptor overexpression in mice skin, reporting no new data but highlighting its link to epidermal atrophy, early barrier formation, eye issues, and hair loss.
1 citations
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June 2013 in “Clinics in dermatology” This review discusses various phytochemicals with potential antialopecia properties and their modes of action, reporting no new experimental results.
December 2025 in “Sains Medisina” This review identified 12 herbal plants producing essential oils with pharmacological activities that stimulate hair growth, potentially through enhanced scalp microcirculation, inhibition of 5α-reductase, anti-inflammatory and antioxidant effects, anagen phase stimulation, and increased dermal papilla cell proliferation.
54 citations
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April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” This review discusses 46,XY disorders of sex development caused by defects in androgen production and highlights the need for long-term care from experienced multidisciplinary teams, but it reports no new clinical findings.
May 2023 in “Journal of Pharmaceutical Research” This article reviews the extensive pharmacological applications of various parts of the neem plant, such as anticancer, anti-inflammatory, and antimicrobial effects, and reports no adverse effects except for allergic reactions, concluding neem is broadly beneficial with numerous medicinal and cosmetic uses.
May 2002 in “Therapeutische Umschau” This article reviews existing treatments for hypertrichosis and hirsutism, noting that while eflornithine is a promising new option, the efficacy of systemic antiandrogens remains unproven in modern clinical studies.
2 citations
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June 2020 in “Journal of Applied Pharmaceutical Sciences and Research” This study reported an association between the rs6259 polymorphism affecting SHBG levels and PCOS in most Indian women, suggesting a potential genetic link in this population.
6 citations
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November 2001 in “Der Hautarzt” This article reviews new developments in hypertrichosis treatments and reports no new clinical results; permanent depilation by photothermolysis and eflornithine cream are highlighted as promising options.
2 citations
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February 2024 in “STAR Protocols” In this research, an optimized protocol was developed for dissociating human scalp tissue to produce high-quality single-cell suspensions suitable for single-cell RNA sequencing, aimed at studying the transcriptomics of human hair follicles.
2 citations
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October 2023 in “Biology” This review highlights cobalt's essential role in vitamin B12 metabolism and its biomedical applications but also warns of health risks from high levels and environmental contamination, discussing remediation methods like phytoremediation.
December 2022 in “Zenodo (CERN European Organization for Nuclear Research)” In this integrative literature review, the researchers reported that finasteride appears highly effective for treating androgenetic alopecia and acne, showing notable benefits after brief treatment durations, though careful dose management is required due to potential sexual side effects.
January 2018 in “Journal of Diabetic Association Medical College.” This case study reports a two and a half-month-old with biotinidase deficiency who showed rapid seizure improvement with biotin treatment after presenting with convulsions and neurological symptoms.
June 1998 in “Pathophysiology” This summary offers an overview of selenium's forms, its biological roles, and dietary sources, but reports no specific research findings.
49 citations
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November 2016 in “Frontiers in Pharmacology” This study found that over 26% of patients using Tripterygium wilfordii Hook F experienced adverse events, highlighting the need for better strategies to manage these risks.
46 citations
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January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Insig deficiency in the skin of mice causes cholesterol precursors to accumulate, leading to defective hair development and skin abnormalities, which were alleviated by simvastatin treatment.
28 citations
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May 2020 in “BMC plant biology” This study concluded that GLCAT14A-C genes are crucial for the function of glucuronic acid transfer to AGPs in Arabidopsis, affecting various growth and reproductive traits such as seed germination and root hair growth.
1 citations
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February 2005 in “The Lancet” Hair loss may be linked to cardiovascular health problems.
1 citations
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October 1996 in “Journal of Cutaneous Medicine and Surgery” This review discusses the advancements needed for gene therapy to become commonly used in dermatology and reports no new clinical results.
April 2020 in “The FASEB Journal” This study found that disrupting testosterone biosynthesis in male rats mitigated cardiovascular and autonomic impairments caused by endotoxemia, indicating testosterone's significant role in these conditions.
September 2020 in “Nature, Environment and Pollution Technology/Nature, environment and pollution technology” This study found that Wistar rats fed with grass extracts from mining areas accumulated trace metals, particularly in the spleen, leading to organ pathology and signs of toxicity.
15 citations
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January 2015 in “Clinical and Experimental Reproductive Medicine” This study reports that obesity significantly influences cardiovascular and metabolic disturbances in women with PCOS, with overweight women experiencing more severe symptoms compared to their non-obese counterparts.
5 citations
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July 2014 in “Acta Crystallographica Section D-biological Crystallography” This study reports that mutations in human L-PGDS affect the entrance and exit of ligands in its binding cavity, suggesting these residues play a role in ligand interaction processes.
April 2022 in “JOURNAL OF RESEARCH AND REVIEW IN SCIENCE” This review examines existing scientific literature on African plants with anti-cancer properties and reports no new experimental results.
January 2017 in “Indian journal of drugs in dermatology” This article reviews the use of saw palmetto extract from a dermatologist's perspective, discussing its traditional role in treating androgenic alopecia and other androgen-related dermatological conditions, but it does not report specific research findings or results.
January 2019 in “Dermatologica Sinica” This study observed that dutasteride treatment led to improvement in acne vulgaris among two male patients with androgenetic alopecia, suggesting its potential as a treatment option for concurrent conditions.
17 citations
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January 2024 in “Journal of Materials Chemistry B” In this study, researchers developed a hyaluronic acid-coated copper peroxide nano-antimicrobial system that demonstrated precise antimicrobial activity and accelerated wound healing by releasing reactive oxygen species in response to bacterial enzymes, in both laboratory and animal tests.
March 2026 in “Journal of Enzyme Inhibition and Medicinal Chemistry” This review examines the development and challenges of using PROTACs, a targeted protein degradation strategy, to treat cancer by degrading specific proteins like PARPs and GPX4, highlighting issues such as target diversification and bioavailability.
This study found that new methods for isolating human dermal papilla cells were more efficient than traditional methods, maintaining higher levels of specific markers and improving the cells' research potential.