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Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Different types of skin cells play specific roles in development, healing, and cancer.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hair loss needs more research for better treatments.

Some medicinal plants can help heal wounds and may lead to new treatments.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Estrogen therapy can reduce skin aging but has cancer risks.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.