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The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Oxidative stress contributes to hair graying and loss as we age.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Postinflammatory hyperpigmentation causes dark skin patches and needs personalized treatment.

Skin-derived precursors in hair follicles come from different origins but function similarly.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

PRP shows potential for treating female hair loss, but more research needed.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

The p53 protein helps control hair follicle shrinking by promoting cell death in mice.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.

Minoxidil treats high blood pressure and side effects can be managed.

Alopecia in captive rhesus macaques is affected by season, sex, age, housing, and stress, with complex links between stress hormones and hair loss.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.

Autophagy is important for human hair growth and health.

Hydrogen peroxide can cause scars by changing healing processes and increasing certain protein levels.

The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.

Apigenin may help promote hair growth and could treat hair loss.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.

Combining cyclosporine A and ketoconazole can effectively treat anal furunculosis in dogs, with some experiencing recurrences and mild side effects.

These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.