19 citations,
October 2017 in “The FASEB Journal” Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.
13 citations,
June 2020 in “Stem Cells International” A substance from a specific gel helped to grow hair effectively in mice, suggesting it could potentially be used to treat hair loss in humans.
9 citations,
November 2012 in “Archives of Dermatological Research” MC4R gene variants not linked to female hair loss.
6 citations,
April 2017 in “Journal of Dermatological Science” Ovariectomized mice mimic postmenopausal hair loss, and estradiol helps maintain hair density.
4 citations,
November 2009 in “Medical Clinics of North America” Stress, nutritional issues, and chronic diseases can cause hair loss, and nail changes may signal internal diseases; treatment focuses on the underlying cause.
November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” The 2004 hair research meeting presented new findings on hair cell differentiation, genetic factors in hair loss, hair pigmentation, and potential targeted therapies.
January 1998 in “KAGAKU TO SEIBUTSU” The document suggests that male hormones likely affect hair growth and baldness, and future treatments might involve stem cells and androgen-independent cells.
521 citations,
January 1954 in “Physiological Reviews” Hair growth is cyclic and influenced mainly by local factors.
117 citations,
November 2006 in “Experimental Dermatology” The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
91 citations,
May 2003 in “American Journal of Pathology” Prolactin affects hair growth cycles and can cause early hair follicle regression.
71 citations,
October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” HFMs can help study hair growth and test potential hair growth drugs.
36 citations,
November 2009 in “Journal of Investigative Dermatology” Prolactin may affect hair growth differently based on gender and scalp area.
17 citations,
May 2010 in “Journal of Dermatological Science” Erythropoietin helps hair grow and could be a potential treatment for hair loss.
13 citations,
January 2010 in “Advances in Biochemical Engineering / Biotechnology” Understanding hair biology is key to developing better treatments for hair and scalp issues.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” The document concludes that treatments like oral anti-androgens, minoxidil, and topical spironolactone can be effective for hair loss in men and women.
212 citations,
September 2015 in “Journal of Investigative Dermatology” The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.
159 citations,
July 2006 in “Endocrine Reviews” Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
130 citations,
August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
130 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).
37 citations,
April 2011 in “Journal of Biological Chemistry” LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
33 citations,
September 2017 in “Molecules” Red ginseng oil and its components help promote hair regrowth and could treat hair loss.
22 citations,
November 2007 in “Journal of Investigative Dermatology Symposium Proceedings” Hair growth and health are influenced by stress and hormones.
19 citations,
April 2019 in “Journal of the European Academy of Dermatology and Venereology” Acne lesions start with changes in hair follicles and increase in inflammation, suggesting a cycle that could affect treatment strategies.
17 citations,
October 2013 in “Plastic and reconstructive surgery. Global open” Male pattern baldness may be caused by scalp pressure on hair follicles, which increases with age and leads to a cycle of hair loss. This process is not directly determined by genes.
11 citations,
May 1990 in “Journal of Dermatological Science” Diazoxide applied to the skin can increase hair growth without harmful side effects.
9 citations,
August 2014 in “European journal of ophthalmology” PGF2α receptors in human eyelids are found in specific parts of hair follicles, explaining eyelash changes with glaucoma treatment.
6 citations,
April 1996 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.
June 2024 in “Sohag Medical Journal” Vitamin D is linked to hair health, but more research is needed for its use in treating female hair loss.
126 citations,
January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
68 citations,
March 2018 in “Biomaterials” Tiny needles with valproic acid can effectively regrow hair.