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Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.

Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.

Hair follicle regeneration needs special conditions and young cells.

Frog skin cells need the protein desmoplakin for proper development and cell layer formation.

After skin injury, adult mice can grow new hair follicles, and this process can be increased or stopped by manipulating Wnt signals.

Hair can regrow in adult mice's skin after injury, and this regrowth doesn't come from existing hair cells but from skin cells in the wound, with Wnt7a protein helping this process. This could help treat baldness and scarring.

Hair can regrow in adult mice's skin after injury, and this regrowth doesn't come from existing hair cells but from skin cells in the wound, with Wnt7a protein helping this process. This could help treat baldness and scarring.

Stem cells can rejuvenate skin, restore hair, and aid in wound healing.

New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.

Different body areas in mice produce different hair types due to interactions between skin layers.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.

Immune cells are essential for early hair and skin development and healing.

Hair can regrow in adult mice's skin after injury, and this process can be boosted by increasing Wnt7a, a protein. This could potentially help treat baldness and change our understanding of hair growth.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

Activating β-catenin in certain skin cells speeds up hair growth in mice.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.

Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.

Hedgehog signaling in skin cells is crucial for hair growth and skin healing, but needs to be balanced to avoid harmful effects like scarring and cancer.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.