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This preclinical study found that exercise-induced extracellular vesicles delayed breast cancer tumor growth in mice, potentially by enhancing the immune response within the tumor microenvironment.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

This study found that patients, oncologists, and payers prioritize a significant improvement in efficacy to justify the added risks and costs when considering CDK4/6 inhibitors combined with endocrine therapy for early-stage breast cancer.

This review discusses the efficacy and safety of exemestane as a treatment for estrogen-receptor-positive breast cancer and reports no new clinical results.

This study found that in men with sexual dysfunction, use of 5ARI may reduce sexual drive and spontaneous erections without worsening pre-existing erectile or ejaculatory issues.

This study found that removing PPARγ specifically from mouse adipose tissue led to severe fat loss, insulin resistance, diabetes, and associated metabolic abnormalities.

This review explores the novel roles of white adipose tissue in tissue homeostasis and regeneration, emphasizing its impact on epithelial, muscle, and immune tissues, and reports no new clinical results.

This review provides an overview of the physiologic skin changes during pregnancy but reports no new findings, emphasizing the need for physicians to distinguish between benign and potentially pathological conditions.

In this retrospective study, cyproterone acetate treatment in late-pubertal trans-girls was found to be generally safe and led to mild feminizing effects, with more rapid feminization occurring when combined with estrogens.

This review details the expression and diverse functions of melatonin receptors in non-neural tissues and reports no new clinical findings, emphasizing their potential as therapeutic targets across various physiological and pathological processes.

This article reviews the similarities in early development processes of hair follicles, teeth, and mammary glands and reports no new experimental findings.

This study found that a 3D wound model, the 3DWoundSE, showed improved responsiveness to injury and cytotoxic stimuli compared to an intact 3D skin equivalent, offering a reproducible and ethical alternative to animal models for early wound response assessment in dermatological research and drug development.

This study found that chemotherapy in female breast cancer patients caused significant early hair loss, which began to recover three months after completion, whereas tamoxifen did not affect hair growth.

This study suggests that breast cancer-associated phospholipids may alter the X-ray diffraction pattern of hair, potentially enabling the development of a sensitive and specific screening test for breast cancer.

The abstract reports no new results but discusses Berry's belief that most changes in breast cancer incidence are due to screening, measurement adjustments, or hormone use.

In this experimental study, researchers developed and optimized metformin-loaded mucoadhesive microspheres for sustained anti-hyperglycemic and anticancer activity, demonstrating high entrapment efficiency, enhanced α-amylase and α-glucosidase inhibition, improved cytotoxicity against breast cancer cells, and promising stability.

This study found that certain endocrine factors, influenced by smoking, birth order, and frequency of orgasms, may play an important role in the development of male breast cancer.

This source discusses the complexity of cancer research, emphasizing that despite extensive studies, a comprehensive understanding of metastatic progression and therapeutic development remains elusive, and underscores the importance of animal models in breast cancer research.

This study found that metabolism-related genes significantly impact the prognosis and metastasis in breast cancer, and the development of prediction models may guide personalized therapeutic strategies.

This paper discusses the role of Runx1 in epithelial biology and pathology, highlighting its dual function as a tumor promoter and suppressor in different contexts, and reports no new experimental findings.

This study found that EGR1 promotes the proliferation of dermal papilla cells, suggesting its close association with hair follicle growth and development.

This review discusses the diagnosis, management, and hormone treatment of transsexual individuals, and examines the risks and effects of cross-sex hormone therapy without presenting new clinical results.

This review discusses factors influencing the earlier onset of puberty, such as obesity and exposure to endocrine-disrupting chemicals, and emphasizes the need for further research and public health policy development.

Breast cancer survivors may have a higher risk of falls, tamoxifen could prevent breast cancer and deaths, new guidelines urge caution with prostate cancer therapy, and early balding in men may indicate a higher prostate cancer risk.

This review discusses developments in oral contraceptives, highlighting improved individualization, reduced side effects, and enhanced suitability for various women's health needs, but it reports no new clinical results.

This study found that keratin K14 expression occurs early in epidermal cell differentiation, while a hair-specific keratin is expressed later in hair matrix cells, suggesting developmental divergence between the two cell types.

This study reported that subcutaneous trastuzumab improved certain symptoms and did not negatively impact health-related quality of life in patients with early or metastatic HER2-overexpressing breast cancer.

This study found that both scalp cooling systems and chemical cooling caps effectively reduced chemotherapy-induced alopecia in early breast cancer patients, with scalp cooling showing better early efficacy but chemical cooling providing greater psychological and quality of life benefits.

This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.

This review highlights the possible impact of side effects from endocrine therapy on quality of life, emphasizing that these can lead to poor adherence and early treatment discontinuation in patients with hormone receptor positive early breast cancer, potentially worsening survival outcomes.