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Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Both mouse and rat models are effective for testing alopecia areata treatments.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

Cosmetics enhance beauty, fix defects, and intimidate enemies, with varying cultural standards and alternative methods.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Low-Level Laser Therapy (LLLT) is a safe and effective treatment for common hair loss, but more research is needed to find the best power and wavelength for treatment.

Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.

Two patients with porphyria cutanea tarda experienced their grey hair turning dark again.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Combined microneedling and minoxidil improves hair growth more than minoxidil alone.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

New acne treatments show promise as alternatives to traditional therapies.

Managing PCOS is hard because it varies a lot, treatments are limited, and there's a lot of false information online.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.