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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.

More pediatric-specific research and guidelines are needed to improve hidradenitis suppurativa treatment in children and adolescents.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

Social housing is a system for those with limited financial resources, needing subsidies and an allocation system, with Germany fitting this criteria.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

The 2018 update to the ED care model added a new severity score and stressed a detailed evaluation of both physical and psychological aspects.

Certain molecules in hair change with age and could be used for cosmetic treatments.

Germany recognizes skin cancer from UV exposure as an occupational disease, emphasizing prevention and care for affected workers.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

Women with Polycystic Ovary Syndrome (PCOS) have a lower health-related quality of life, especially those with an anovulatory phenotype, and may need specific interventions to improve it.

Giving dihydrotachysterol to mother rats caused skin hardening and bone issues in their babies through milk.

Lack of cystatin M/E causes thin hair and dry skin.

HSP90 and lamin A/C are crucial for hair growth and could be targets for treating hair loss.

Alfatradiol (0.025%) is an effective and safe treatment for hair loss in both women and men.

A hospital outbreak of catheter infections in calves was caused by a bacteria from a beef herd, leading to longer hospital stays, more drug use, and calf deaths.

Porphyra-334 may help reduce wrinkles and promote hair growth.

Stephen Rothman made important discoveries in dermatology, including the use of PABA in sunscreens, but never profited from his work.

Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.

A 23-year-old woman with Hashimoto’s thyroiditis improved significantly after a 15-month integrative treatment plan.

Some horses lose hair without inflammation or itching due to various conditions, and while mainly a cosmetic issue, diagnosis requires examination and biopsies, and breeding is not advised if it's hereditary.

The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.

Diagnosing and managing PCOS in teens is hard, but early diagnosis and lifestyle changes are key, and more research is needed for long-term health.

Hair follicle stem cells might help treat traumatic brain injury.

Iron levels are linked to insulin resistance in men and postmenopausal women, but not in premenopausal women.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

Eosinophilia-myalgia syndrome, linked to contaminated L-tryptophan supplements, caused severe symptoms and some deaths, with long-term effects in survivors.