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Ixekizumab helps improve life quality, physical ability, and work performance in patients with psoriatic arthritis who haven't used biologic drugs before.

Frailer men have a higher risk of worsening prostate problems and serious health events needing hospital care.

Ixekizumab is effective and safe for patients who did not improve with etanercept treatment for psoriasis.

Lichen planus may be associated with a higher risk of metabolic syndrome.

Testosterone therapy increases bone density in older men with low testosterone levels.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).

PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.

Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.

Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.

A hormone linked to collagen helps hair grow back in mice after chemotherapy, and may also prevent bone loss.

A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.

Three siblings with a genetic form of rickets showed different symptoms of the disease.

People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.