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This narrative review reflects on the challenges faced by FDA's Oncologic Drugs Advisory Committee members, highlighting public pressure, decision-making complexity, and the evolving landscape of cancer drug development.

This case report highlights a novel NR5A1 gene variant associated with a severe 46,XY disorder of sex development, stressing the importance of genetic screening in similar cases.

This study investigated the cytotoxic effects of DHA derivatives on cancer cell lines and found that didocosahexaenoin was the most potent, inducing apoptosis and producing reactive oxygen species in PC3 prostate carcinoma cells.

This study found that a lipid-based nanoparticle formulation with oleic acid for delivering dutasteride showed lower skin permeation compared to a formulation without oleic acid, indicating its potential for targeted dermal delivery.

This study examines how conditions like PSSD, Long COVID, and ME/CFS form a "Post-Exposure Syndromes" family, initiated by transient exposures but persisting due to complex state-space dynamics, and suggests improving pharmacovigilance to better address and understand these persistent syndromes.

This study identified two genome-wide significant genetic associations with seborrheic dermatitis, suggesting a potential genetic susceptibility contributing to the disease's pathogenesis.

This case study suggests that genetic susceptibility to PCOS and rare syndromes, such as Trichorhinophalangeal syndrome Type 1, should be considered in young men with unexplained hyperandrogenism.

R-spondin2 may help treat hair loss, gene differences could explain baldness, a peptide's regulation is linked to psoriasis, B-defensin gene copies may affect a skin condition's risk and severity, and potential markers and targets for alopecia areata were identified.

In this study, researchers identified PSENEN mutations that can lead to a form of Dowling-Degos disease, characterized by follicular hyperkeratosis and an increased susceptibility to acne inversa, especially in the presence of certain trigger factors.

This content only provides information about the JAMA Dermatology publication platform and reports no research results.

This letter discusses three plasmacytoid dendritic cell-related parameters that may help differentiate lupus alopecia from lichen planopilaris, but it reports no new study results.

In this prospective observational study of 96 dermatomyositis patients, 47 showed scalp involvement, with significant symptoms like scalp inflammation, itching, and hair loss linked to myositis-specific antibodies. The study highlighted unique dermatopathological features in the scalp and emphasized the considerable morbidity caused by scalp dermatomyositis.

This case series reports the specific dermoscopic features observed in two patients with syphilitic alopecia, highlighting alopecic patches with empty hair follicles and other distinguishing characteristics that may aid in differentiating it from other hair disorders.

This study found that adipose-derived stem cell exosome injections were more effective than minoxidil in improving hair density and diameter in patients with androgenetic alopecia, with high patient satisfaction and manageable side effects.

In this study, DOP treatment improved hair regrowth in androgenetic alopecia by altering local steroid metabolism and follicular morphology.

This commentary discusses ethical concerns with direct-to-consumer teledermatology services, highlighting potential conflicts of interest and issues with care quality.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

This report describes two South Australian Poll Hereford calves with a syndrome of congenital dyserythropoietic anaemia, dyskeratosis, and progressive alopecia, observing specific blood and bone marrow abnormalities.

In this South Korean retrospective study, dutasteride improved hair growth more effectively than finasteride in men with androgenic alopecia, and had a similar or possibly lower rate of adverse events, suggesting it as a viable treatment option.

In this research, sequencing the chloroplast genomes of 10 Sansevieria trifasciata cultivars allowed the identification of a trnT-psbD deletion marker capable of distinguishing closely related species, and highlighted evolutionary links with Dracaena, contributing molecular tools for taxonomy and phylogenetic studies in Asparagaceae.

This archive discusses the history and purpose of the Bioline International platform for disseminating scholarly research from developing countries, but reports no new research findings.

Hair diameter diversity helps assess hair loss, but its standard measure varies by individual and ethnicity.

This article offers dermoscopic comparisons between fibrosing alopecia and androgenetic alopecia with seborrheic dermatitis but reports no new research findings.

This paper from dermatology experts discusses their affiliations and declares no significant commercial interests, but it reports no research findings.

This case report describes a patient with secondary syphilis exhibiting distinct dermoscopic features, including moth-eaten alopecia and an erythematous background more pronounced than previously reported.

This study describes a capillary GC method for accurately measuring spermidine levels in hair lotions, confirming its precision and specificity for this application.

The ZIP13 variant is linked to abnormal hair quality.

This study describes three adult dogs with sebaceous gland dysplasia, reporting that two showed moderate to marked improvement in symptoms with treatment, though ongoing management is required as the condition cannot be cured.

This study found that SPARC-overexpressing adipose-derived mesenchymal stem cells significantly improved various aspects of skin wound healing in dogs, including re-epithelialization, collagen deposition, and angiogenesis, showing promise for enhancing treatment effectiveness under different physiological and pathological conditions.

This study found a perfect correlation between laser Doppler velocimetry measurements of scalp blood perfusion after minoxidil application and sulfotransferase enzyme activity in hair follicles, indicating a potential non-invasive test to predict minoxidil response in female pattern hair loss.