Zinc Transporter ZIP13 G289R Variant From Spondylocheirodysplastic Ehlers-Danlos Syndrome Is Associated With Abnormal Hair Quality

A 36-year-old man with androgenetic alopecia suspects copper and zinc deficiencies may be accelerating hair loss and is supplementing copper to address this. He is also monitoring blood sugar levels due to previous prediabetes concerns and plans to test for insulin resistance.

Zinc supplementation caused significant hair shedding for the user, who had been successfully managing hair loss with finasteride, minoxidil, RU58841, and microneedling. The user discontinued zinc after noticing no libido increase and believes the hair loss was due to zinc's interaction with other minerals or hormonal changes.

Zinc supplements may slightly increase DHT by affecting testosterone conversion, but are generally beneficial for health. A 15mg Zinc to 1mg Copper ratio is recommended.

The conversation discusses hair loss and bloodwork results, focusing on zinc, vitamin D, and ferritin levels. The user is experiencing telogen effluvium after surgery and seeks advice on supplementation.

Iron and zinc vitamins helped improve hairline regrowth for someone with celiac disease. Nutrient deficiencies, like iron, can contribute to hair loss, especially around the temples.

A 20-year-old male is concerned that zinc might reduce the effectiveness of finasteride for hair loss, as zinc is known to increase DHT levels. Users suggest that zinc, at certain doses, has anti-androgenic properties and is unlikely to negatively impact finasteride's efficacy.