14 citations
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May 2021 in “Marine Drugs” This review discusses the therapeutic properties of polydeoxyribonucleotides derived from marine organisms for wound healing and inflammation, but it reports no new clinical results.
July 2026 in “Skin Appendage Disorders” In this study, patients with treatment-refractory alopecia areata who received oral ritlecitinib 50 mg daily experienced significant hair regrowth, with 52.6% achieving complete scalp regrowth and improved Severity of Alopecia Tool scores, indicating its potential effectiveness in real-world settings.
August 2025 in “Journal of the American Academy of Dermatology”
25 citations
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August 2014 in “Endocrinology” This study created a humanized mouse model of hereditary vitamin D-resistant rickets that lacks alopecia, indicating the mutant receptor's potential to explore the syndrome's characteristics beyond vitamin D binding.
13 citations
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June 2017 in “Biochimie open” This study determined that the human steroid 5α-reductase enzymes localize to the endoplasmic reticulum in HeLa cells, with protein tagging affecting expression and inducing protein aggregates for some isoforms.
1 citations
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January 2018 in “International Journal of Clinical and Developmental Anatomy” This study highlights that including scalp dermoscopy in diagnosing patients treated with the Regenera® protocol revealed that expected outcomes were often overestimated for those with poor prognosis.
13 citations
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November 2013 in “Journal of Endocrinology/Journal of endocrinology” This study found that the vitamin D receptor, but not its ligand, regulates genes involved in hair cycle progression, suggesting a role in integrating hormone signaling pathways for hair and epidermal functions.
11 citations
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August 2010 in “Developmental neurobiology” This study suggests that Ptprq in the hair bundles may exist as multiple isoforms that are differentially expressed throughout development and affect the organization of stereocilia in the chick inner ear.
16 citations
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September 2019 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that the retinol dehydrogenases SDR16C5 and SDR16C6 in mice play a crucial role in skin retinol dehydrogenase activity, affecting hair growth and gland functions without impacting survival.
4 citations
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April 2014 in “Lasers in Surgery and Medicine” This observational study reports that a TRASER device using specific wavelengths for vascular and follicular targets showed both clinical responses and histological changes, suggesting its potential as an effective vascular and hair removal tool.
August 2025 in “Therapeutics” In this study, low concentrations of DMSO were found to decrease androgen receptor expression and inhibit the migration of prostate cancer cells, suggesting potential as an anticancer therapy.
March 2026 in “SKIN The Journal of Cutaneous Medicine” This study found that ritlecitinib was well tolerated in children aged 6 to under 12 years with severe alopecia areata, with ongoing trials examining its efficacy and safety over a 24-week period and in long-term use up to 36 months.
9 citations
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August 1980 in “Journal of Cutaneous Pathology” This study found that Rhodamin B staining of keratin was inconsistent across normal skin, epithelial tumors, and dermatoses, with notable differences in staining intensity between tricho-hyalin and keratohyalin granules.
78 citations
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November 2005 in “Endocrinology” This study found that Hairless (Hr) acts as a corepressor of the vitamin D receptor (VDR) in human keratinocytes, blocking the action of vitamin D on keratinocyte differentiation.
May 2023 in “JAAD international” This study evaluated the clinical outcomes of using tattoo equipment to deliver a combination of minoxidil and dutasteride directly to the scalp over three sessions for treating male androgenetic alopecia, but results are not reported in the abstract.
July 2012 in “The Journal of Urology” This abstract reviews testosterone supplementation with and without a dual 5α-reductase inhibitor on fat-free mass in men with suppressed testosterone production and reports no new research findings.
53 citations
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December 2012 in “Revista da Sociedade Brasileira de Medicina Tropical” In this study, liver transaminase levels and various symptoms persisted in some adult dengue patients even two months after diagnosis.
31 citations
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January 2008 in “Gynecological endocrinology” In this study, two different estroprogestin treatments significantly improved skin conditions and decreased androgen levels in hyperandrogenic women, with EE/DRSP showing more pronounced hormonal changes and skin improvements compared to EE/CMA.
In this summary, the researchers describe the Brazilian keratin treatment as a popular hair-straightening process that originated in Brazil in 2003 and has since gained global traction, particularly for smoothing and straightening curly or frizzy hair through a keratin-based product and heat application.
October 2022 in “Revista Eletrônica Acervo Médico” This narrative review discusses adverse effects associated with 5-ARI treatments for male-pattern baldness and benign prostate hyperplasia, including sexual health, neurological, endocrine, metabolic, and cardiovascular impacts, and emphasizes careful prescription assessment.
33 citations
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December 2005 in “British Journal of Clinical Pharmacology” This study found that the Transdermal Delivery System efficiently delivers testosterone systemically and showed bioequivalent hormone concentrations to a known topical gel in healthy males.
September 2022 in “Research Square (Research Square)” In this study, the DIET-AI model, developed from a large dataset of over 200,000 images, demonstrated diagnostic performance for 31 skin diseases comparable to dermatologists of varying experience levels in 15 hospitals across China, supporting its potential effectiveness in clinical settings.
April 2017 in “The Journal of urology/The journal of urology” This study observed that both dutasteride and finasteride affected penile morphology in normotensive and hypertensive rats, with more pronounced changes in hypertensive animals, especially when treated with dutasteride.
4 citations
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February 2024 in “Dermatology and Therapy” The study found that a single autologous micrografting treatment using Rigenera® technology significantly improved the appearance of stretch marks in healthy women after three months, showing greater enhancements in skin properties compared to microneedling alone.
1 citations
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June 2012 in “Revista Brasileira de Cirurgia Plástica” In this study, the authors reported that frontal rhytidectomy with a pre-hairline incision effectively reduces a long forehead in select patients, with patients feeling the benefits outweighed the visibility of the scar.
2 citations
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June 2024 in “Parasites & Vectors” This study provides insights into how chronic T. gondii infection might affect testicular tissue and suggests a potential impact on male fertility.
29 citations
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July 2009 in “BJU international” This review examines the pharmacological properties and potential clinical benefits of 5α‐reductase inhibition in prostate cancer but reports no new research findings.
January 2023 in “The Egyptian Journal of Hospital Medicine” This review discusses the potential of platelet-rich plasma as a new and promising treatment for striae distensa, noting its lack of associated risks like hyperpigmentation or infection, but reports no clinical results.
24 citations
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September 2002 in “Der Urologe” A stronger dual 5α-reductase inhibitor could improve treatment for benign prostatic hyperplasia by further reducing DHT levels.
28 citations
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November 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study indicates that the normal human prostate is not a major contributor to circulating blood DHT concentrations in androgen-deficient patients receiving testosterone replacement therapy.