Traser: Acute Phase Vascular And Follicular Changes

The study investigated the use of a TRASER device, which utilizes energy from a flashlamp to induce photon emission from a fluorescent medium, for targeting vascular and hair follicle structures. The research involved treating skin with two different fluorescent media, Pyrromethene 556 for vascular targets and Sulforhodamine 640 Chloride for hair follicles, on subjects with photo type II skin. Results showed a purpuric response at 7.2 J/cm2 for vascular targets, with histological evidence of intravascular thrombosis without extravasated red blood cells. For hair follicles, perifollicular edema and transient erythema were observed, similar to standard hair removal lasers, with histological changes limited to target structures. The study concluded that TRASER could effectively target vascular and hair structures, demonstrating its potential as a vascular and hair removal device.