Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that extracellular vesicles from low-passage dermal papilla cells may activate hair growth by delivering miR-140-5p, which downregulates BMP2 signaling, suggesting potential therapeutic targets for alopecia.

This study found that Twist1 and Tcf4 synergistically regulate the hair follicle induction ability of dermal papilla cells by forming a complex with β-catenin, enhancing their biological properties.

This article discusses the factors contributing to acne and reports no new findings, focusing on the role of sebaceous lipids and associated processes.

This study found that treating a 3D hair dermal papilla model with rice bran extract and electromagnetic fields increased melanogenesis, suggesting potential for vitiligo and white hair therapies.

In this study, different extracellular matrix types altered growth characteristics of cultured human dermal papillae cells but did not significantly affect their biological function-related characteristics.

This study suggests that mesenchymal stem cell-induced dermal papilla-like tissues can generate new hair follicles in mice, indicating potential for developing hair cell therapy using stem cells.

In this study, researchers established five new immortalized human dermal papilla cell lines from a male with androgenetic alopecia, which may serve as valuable tools for hair research.

This study found that calcium microcapsules exhibited better biocompatibility and cell viability than barium microcapsules for scaffolding in artificial dermal papilla, suggesting potential for developing new hair follicle structures.

This study found that new methods for isolating human dermal papilla cells were more efficient than traditional methods, maintaining higher levels of specific markers and improving the cells' research potential.

This review examines topical immunotherapy for severe alopecia areata, noting that diphencyprone and squaric acid dibutylester are non-mutagenic options with similar efficacy but different practical considerations, and reports no new clinical results.

This study found that minoxidil increased 17ß-hydroxysteroid dehydrogenase activity by nearly 40% in dermal papilla cells from balding scalps but not in nonbalding scalp cells or dermal fibroblasts.

This study found that Rab27a and Rab27b play opposite roles in hair growth, with Rab27a knockdown suppressing and Rab27b knockdown promoting hair growth in models.

This chapter reviews the causes and underlying steroid pathways of hirsutism and virilization in women, detailing relevant conditions and laboratory assays without reporting new clinical results.

This study concluded that the CXCL12–CXCR4 signaling pathway significantly contributes to hair loss in androgenetic alopecia and alopecia areata by promoting inflammation and fibrosis, whereas inhibiting this pathway can restore hair growth and follicle health.

This review examines various pharmacological options for managing alopecia areata, highlighting the effectiveness of corticosteroids for mild to moderate cases and promising results from JAK inhibitors like baricitinib for more severe forms, with additional benefits from minoxidil and potential from other treatments.

This study found that higher concentrations of topical diphenylcyclopropenone, especially when prepared with acetone, showed better stability over 6 months compared to lower concentrations.

This review outlines various complications associated with hair transplantation, noting that while most are mild and manageable, serious complications like necrosis can occur if proper care is not taken.

The conclusion suggests a new treatment for infantile hemangiomas and a potential target for hair loss treatment.

Mycophenolate mofetil improved skin condition in a man with nephrogenic fibrosing dermopathy.

Itch is a common symptom in patients with chronic venous insufficiency, often accompanied by burning and pain.

This article highlights the lack of research on the prevalence and characteristics of pain and itch in early stages of mild to moderate varicose vein disease, without reporting new findings.

This review discusses current experimental approaches for regenerating human hair follicles using tissue engineering and isolated cells, but reports no successful strategies with adult cells yet found.

This study suggests that Houttuynia cordata extract may promote hair growth by stimulating dermal papilla cell proliferation and extending the anagen phase through enhanced energy metabolism and gene expression changes.

This review discusses recent advancements in hair follicle organoid technology for alopecia treatment but presents no new experimental results, emphasizing the potential for clinical applications and drug screening.

This study found that intrinsic feedback loops are crucial for maintaining the function of human dermal papilla cells during hair growth, highlighting the importance of autocrine signaling and niche reprogramming for advancing hair follicle biology and regenerative therapies for hair loss.

3D-oxy exosomes may significantly boost hair growth, offering new treatment options for hair loss.

This study found that hair follicle stem cells in mice have an unexpected ability to adaptively determine their differentiation pathways, maintaining tissue architecture despite external stimuli.

In this study, researchers found that stabilizing the protein HIF1A in hair follicles promotes glycolysis over oxidative phosphorylation, potentially reducing oxidative stress and supporting hair growth.

This study suggests that human hair follicles may operate their own Cori cycle, synthesizing glycogen from lactate under conditions of lactic acidosis.

This case report identifies a novel LIPH gene mutation linked to autosomal recessive woolly hair/hypotrichosis in a Japanese boy, expanding the spectrum of known mutations associated with this condition.