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    Glossary Doxorubicin

    chemotherapy drug that interferes with cancer cell DNA

    Doxorubicin, also known as Adriamycin, is a chemotherapy drug used to treat various types of cancer, including breast cancer, bladder cancer, and lymphoma. It works by interfering with the DNA inside cancer cells, preventing them from growing and dividing. However, it can also cause side effects such as hair loss (alopecia) and damage to the heart, so its use is carefully monitored by healthcare professionals.

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    Research 30 of 783

    1. Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer Annals of oncology · 2004 · 1461 citations
    2. Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy Cancer investigation · 2001 · 522 citations
    3. Pegylated Liposomal Doxorubicin in the Treatment of Breast Cancer Clinical breast cancer · 2003 · 108 citations
    4. Copper−Doxorubicin as a Nanoparticle Cargo Retains Efficacy with Minimal Toxicity Molecular Pharmaceutics · 2010 · 102 citations
    5. Hair Follicle–Derived Blood Vessels Vascularize Tumors in Skin and Are Inhibited by Doxorubicin Cancer Research · 2005 · 76 citations
    6. Prevention of doxorubicin-induced alopedia by scalp hypothermia: relation to degree of cooling. The BMJ · 1982 · 53 citations
    7. Minoxidil (Mx) as a prophylaxis of doxorubicin – induced alopecia Annals of Oncology · 1994 · 49 citations
    8. The circular RNA circNlgnmediates doxorubicin-inducedcardiac remodeling and fibrosis Molecular therapy. Nucleic acids · 2022 · 19 citations
    9. High-dose alpha-tocopherol as a preventive of doxorubicin-induced alopecia. PubMed · 1986 · 18 citations
    10. A medicinal and edible formula YH0618 ameliorates the toxicity induced by Doxorubicin via regulating the expression of Bax/Bcl-2 and FOXO4 Journal of cancer · 2019 · 17 citations
    11. Doxorubicin-induced hair loss in the Angora rabbit: a study of treatments to protect against the hair loss Cancer Chemotherapy and Pharmacology · 1987 · 12 citations
    12. Chemoprevention of doxorubicin-induced alopecia in mice by dietary administration of l-cystine and vitamin B6 Archives of Dermatological Research · 2012 · 11 citations
    13. Chinese Herbal Medicine, Guilu Erxian Glue, as Alternative Medicine for Adverse Side Effects of Chemotherapy in Doxorubicin-Treated Cell and Mouse Models Evidence-based complementary and alternative medicine · 2021 · 9 citations
    14. ANALYSIS OF ADVERSE DRUG REACTIONS (ADRs) AND THEIR SEVERITY IN BREAST CANCER PATIENTS TREATED WITH THE DOCETAXEL-DOXORUBICIN REGIMEN AT SULTAN AGUNG ISLAMIC HOSPITAL Jurnal Farmasi Sains dan Praktis · 2025
    15. Abstract P1-12-19: A case report of successful hair preservation using scalp cooling with doxorubicin and cyclophosphamide during pregnancy Clinical Cancer Research · 2025
    16. iTRAQ-based quantitative proteomics revealing the therapeutic mechanism of a medicinal and edible formula YH0618 in reducing doxorubicin-induced alopecia by targeting keratins and TGF-β/Smad3 pathway Heliyon · 2024
    17. Streptomyces-derived nano-doxorubicin: Clinical status and patents granted Scripta Medica · 2024
    18. Cepharanthine Inhibits Doxorubicin-Induced Cellular Senescence by Activating Autophagy via the mTOR Signaling Pathway Discovery medicine · 2023
    19. Détection précoce de la cardiotoxicité due à la doxorubicine chez le miniporc par imagerie par résonance magnétique PolyPublie (École Polytechnique de Montréal) · 2016
    20. TRAIL sensitization of PC3 prostate cancer cells by doxorubicin can be blocked by the anti-oxidant N-acetyl-cysteine or by the iron chelator deferoxamine Clinical Cancer Research · 2006
    21. A novel derivative of doxorubicin, AD198, inhibits canine transitional cell carcinoma and osteosarcoma cells in vitro Drug Design Development and Therapy · 2015 · 12 citations
    22. Pathogenesis of Hand-Foot Syndrome induced by PEG-modified liposomal Doxorubicin Human cell · 2013 · 63 citations
    23. A phase 1b study of chemo-immunotherapy with pegylated liposomal doxorubicin and Pembrolizumab in estrogen receptor positive metastatic breast cancer Cancer Research Communications · 2026
    24. Effects of Mitoquinone on Doxorubicin-Induced Cytotoxicity in H9c2 Cardiac Myoblasts and 22Rv1 Prostate Cancer Cells Digital Commons - PCOM (Philadelphia College of Osteopathic Medicine) · 2026
    25. The significance of the apelinergic system in doxorubicin-induced cardiotoxicity Heart Failure Reviews · 2024 · 13 citations
    26. Correlation of toxicity with pharmacokinetics of pegylated liposomal doxorubicin (Doxil) in metastatic breast carcinoma Cancer · 2000 · 388 citations
    27. Cytoprotectivity of the natural honey against the toxic effects of Doxorubicin in mice Advances in bioscience and biotechnology · 2014 · 5 citations
    28. Data from A Phase Ib Study of Chemoimmunotherapy with Pegylated Liposomal Doxorubicin and Pembrolizumab in Estrogen Receptor–Positive Metastatic Breast Cancer 2026
    29. A local drug delivery system based on visible light-cured glycol chitosan and doxorubicin⋅hydrochloride for thyroid cancer treatment <i>in vitro</i> and <i>in vivo</i> Drug Delivery · 2018 · 27 citations
    30. Determination of the Effects of Eruca sativa Oil, Sodium Carbonate, Lavender Oil and Aloe vera Oil on Lipid Profile and Breast Tumour Markers in Breast Cancer-induced Doxorubicin Treated Female Albino Rats Annual Research & Review in Biology · 2020 · 2 citations