research Metformin Therapy for the Reproductive and Metabolic Consequences of Polycystic Ovary Syndrome
Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.
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research Nonclassic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency: Pathophysiology, Diagnosis, and Treatment
The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.
research Prostate Cancer Incidence Among Finasteride and Alpha-Blocker Users in the Finnish Prostate Cancer Screening Trial
Finasteride might lower the risk of low-grade prostate cancer but not high-grade cancer, while alpha-blockers might reduce high-grade cancer risk.
research The Pharmacologic Treatment of Muscle Pain
The document concludes that more research is needed to understand how to treat muscle pain with drugs.
research A Randomized Trial of Oral DHEA Treatment for Sexual Function, Well-Being, and Menopausal Symptoms in Postmenopausal Women with Low Libido
DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.
research Improving Translational Research in Sex-Specific Effects of Comorbidities and Risk Factors in Ischemic Heart Disease and Cardioprotection: Position Paper and Recommendations of the ESC Working Group on Cellular Biology of the Heart
The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.
research Preparation and Characterization of Dutasteride-Loaded Nanostructured Lipid Carriers Coated with Stearic Acid-Chitosan Oligomer for Topical Delivery
The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.
research Polymeric Nanoparticles-Embedded Organogel for Roxithromycin Delivery to Hair Follicles
Scientists created a gel with nanoparticles to deliver medicine to hair follicles effectively.
research Kin-Cohort Analysis of LRRK2-G2019S Penetrance in Parkinson's Disease
The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.
research Putative Role for Insulin Resistance in Depression Risk in Polycystic Ovary Syndrome
Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.
research Steroid Plant Hormones: Effects Outside the Plant Kingdom
Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
research A Preliminary Study of Finasteride in Tourette Syndrome
Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.
research Mitoxantrone
Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.
research Clinical Picture, Diagnosis, Treatment, and Outcome of Severe Acute Respiratory Syndrome (SARS) in Children
Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.
research Psychological Interventions in the Management of Common Skin Conditions
Using psychological treatments can help manage skin conditions along with regular medical care.
research Psychodermatology: Emotional Factors and Treatment Approaches
The review suggests that understanding and treating the psychological aspect of skin disorders is important and calls for more collaboration in this field.
research Cyclophosphamide and Rituximab in Frequently Relapsing/Steroid-Dependent Nephrotic Syndrome
Rituximab leads to longer remission and fewer side effects than cyclophosphamide.
research Polycystic Ovary Syndrome in Salvador, Brazil: A Prevalence Study in Primary Healthcare
About 8.5% of women in Salvador, Brazil, have Polycystic Ovary Syndrome.
research Desferrioxamine Treatment of Aceruloplasminemia: Long-Term Follow-Up
Finasteride may help reduce symptoms in male Tourette syndrome patients.
research Positive Lymphocyte Transformation Test in a Patient with Allergic Contact Dermatitis of the Scalp After Short-Term Use of Topical Minoxidil Solution
Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
research Topical ALA-Photodynamic Therapy for Acne Can Induce Apoptosis of Sebocytes and Down-Regulate Their TLR-2 and TLR-4 Expression
ALA-photodynamic therapy helps reduce acne by causing acne cell death and lowering certain skin protein levels.
research Acquired Scalp Alopecia: A Review
Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.
research A Unique Clinicopathological Manifestation of Fungal Infection: A Case Series of Deep Dermatophytosis in Immunosuppressed Patients
Early treatment of superficial fungal infections in immunocompromised patients is crucial.
research Novel Approach to Treating Androgenetic Alopecia in Females With Photobiomodulation (Low-Level Laser Therapy)
Low-level laser therapy effectively treats female hair loss, increasing hair count by 51%.
research Middle East Medicinal Plants in the Treatment of Diabetes: A Review
Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.
research Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date
Finasteride shows promise for female hair loss, but more research needed.
research Gender-Affirming Hormone Therapy for Transgender Females
Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.
research New Steps Forward in the Neuroactive Steroid Field
Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
research Cardiovascular Risk Factors and Events in Women with Androgen Excess
Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.
research Clinical Features of Familial Lewy Body Parkinsonism Caused by α-Synuclein Triplication (Iowa Kindred) with Video Documentation
The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.