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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Stem cells can help regenerate hair follicles.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Exosomes help nerve fibers grow by affecting specific cell signaling pathways.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Rat whisker cells can help turn other cells into nerve cells and might be used to treat brain injuries or diseases.

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.

Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.

The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.

Hair follicle stem cells need all reprogramming factors to become pluripotent.

RANKL improves the immune response against herpes simplex virus by enhancing T cell activation and could help develop better treatments or vaccines.

The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

Innovative methods are reducing animal testing and improving biomedical research.

A specific genetic deletion in goats affects cashmere yield and thickness.

Tiny particles from skin cells can help activate hair growth.

Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.

Human skin can be reconnected to nerves using stem cells, which may help with skin health and healing.

Biologics, especially Dupilumab, are effective and safe for treating severe childhood eczema.

Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.

Different ligands change the shape of the TRPV3 ion channel in unique ways.

Meis2 is essential for touch sensation and nerve function in mice.

The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.

Stress can cause hair loss by affecting nerve-related hair growth, and noradrenaline might help prevent this.

Stem cells in hair follicles can become various cell types, including neurons.

Runx3 helps determine hair shape.