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The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Human liver cells stick to hair protein materials mainly through the liver's asialoglycoprotein receptor.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Certain drugs that block specific enzymes can help treat prostate diseases.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

TGF-β2 plays a key role in human hair growth and development.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.