Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, re-activating SOX9 in adult epidermal stem cells led to a fate switch towards hair follicle stem cell identity, with altered chromatin dynamics and oncogenic activation, contributing insights into developmental processes and cancer pathways.

In this chemical investigation, cyclospongiaquinone 1 from the sponge Verongula cf. rigida showed strong steroid 5α-reductase inhibitory activity, comparable to that of finasteride.

This review summarizes the antioxidant and anticarcinogenic properties of Indian Gooseberry, its phytochemical composition, and its use in traditional Ayurvedic medicine, but reports no new clinical results.

This study used a 3D bioprinted human lung cancer model in a mouse phantom to demonstrate a selective cytotoxic effect of X-rays on tumor cells, revealing differences from 2D cell models.

This study found that mutations in the TULP3 gene are associated with progressive degeneration of the liver, kidney, and heart in adults, highlighting the importance of early detection and management.

This study found that extracellular vesicles derived from 3D cultures of cervical cancer cells have small RNA profiles more similar to those in patient plasma than those from 2D cultures.

This meeting in Heidelberg highlighted diverse contributions on stem cell research, including pre-clinical and clinical applications, but reported no new experimental results.

This study explains that while trichothiodystrophy and xeroderma pigmentosum share genetic defects, TTD patients primarily exhibit issues in transcription initiation, not the increased skin cancer risk seen in XP.

This review emphasizes that collaboration between forensic anthropology and molecular anthropology could significantly improve the identification of unknown human remains by creating more comprehensive biological profiles.

This study found that regular yoga practice could benefit women with PCOS by improving hormonal balance, mitochondrial health, oxidative stress, and inflammation, while also reducing depression symptoms, suggesting yoga as a supportive therapy for managing PCOS.

This study found that papillary dermal fibroblast progenitors in newborn mouse skin can be isolated and cultured to generate male germline cell precursors, demonstrating their potential through differentiation into cells with meiotic capability.

This review discusses the role of zinc and its transporters in skin health and disorders, providing an overview without presenting new clinical results.

This case study reports the first clinical case of besnoitiosis in two donkeys in Italy, suggesting a wider distribution of the disease in European equids than previously expected.

This case report highlights a rare presentation of acute lupus hemophagocytic syndrome with initially negative antinuclear antibodies, underscoring the higher sensitivity of the 2012 Systemic Lupus International Collaborating Clinics criteria for diagnosis.

This study describes a case of cyclic thrombocytopenia where a novel MPL gene mutation may contribute to the disease, with gene expression changes in platelet and neutrophil genes preceding platelet count fluctuations.

This study observed that gene expression differences in Rex rabbits with varying wool densities suggest the involvement of specific genes and signaling pathways, including Shh and Eph, in hair follicle development.

This study found that while some extracts from DanGuiBoHyulTangGami-Bang showed potential in inhibiting 5-reductase type Ⅱ and had antioxidant activity, they were not effective in extending the hair growth period.

This case report describes a rare instance of dermatophytosis in a young cat caused by Microsporum gypseum, confirmed by molecular analyses to be Arthroderma gypseum.

This review discusses the potential antiaging effects of Chinese herbal medicines and suggests their role in regulating aging-related genes through various signaling pathways; it reports no new clinical results.

This study found that the Wnt-β-catenin pathway directly promotes TERT expression in both stem and cancer cells, highlighting a mechanistic link between tumorigenesis and pluripotency.

This research reports that copper-quercetin complexes show strong potential in antioxidation and cancer therapy, while their effects on specific cell death pathways warrant further investigation.

This study reported a case where a 46-year-old woman developed alopecia without itching or pain on her scalp due to a cutaneous infection from *Mycobacterium abscessus*, which was resolved after three months of antibacterial treatment, resulting in new hair growth.

This case report presents the first Russian patient with Meier-Gorlin syndrome 5, expanding clinical understanding through the identification of two novel CDC6 gene variants.

This study suggests that residues Val-889 and Arg-752 in the androgen receptor's steroid binding domain are crucial for NH2-/carboxyl-terminal interaction, affecting receptor stability and function.

This review highlights the potential of integrating point-of-care testing with allele-specific amplification techniques like AS-PCR, AS-LAMP, and AS-RPA to improve the efficiency, accuracy, and affordability of genotyping single nucleotide polymorphisms associated with human diseases.

This case report documented a novel presentation of a canine viral plaque appearing as a solitary exophytic keratin-filled mass, highlighting the need to differentiate it from a hair follicle tumor.

In this study, finasteride was shown to inhibit glioma stem-like cells and reduce glioblastoma proliferation, suggesting its potential as an anti-glioblastoma drug.

This case report describes proguanil-related hematologic toxicity in a patient on peritoneal dialysis, suggesting that this malaria prophylaxis should be avoided in chronic kidney disease due to proguanil accumulation.

This case report describes an 18-year-old girl with systemic lupus erythematosus who developed lupus pneumonitis, initially misdiagnosed as tuberculosis, and responded dramatically to corticosteroid treatment.

In this study, NGF and minoxidil increased the growth of human hair follicles while 17 beta-E2 inhibited it; NGF also neutralized 17 beta-E2's inhibitory effect.