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Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

SV40 T antigen in hair follicles causes abnormal hair and health issues in mice.

Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.

New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

The document explains the genetic causes and characteristics of inherited hair disorders.

Eating less can improve stem cell function and increase lifespan.

Alk1 in specific cells is crucial for proper nerve branching and hair function.

Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.

African American women have a higher risk of preterm delivery than Caucasian women, and inflammatory stimuli affect gene expression in cells related to PCOS, showing a heightened inflammatory state in women with PCOS.

Low-level laser therapy may help stem cells grow and function better, aiding in healing and tissue repair.

Found key genes affecting hair loss, immune response, and skin development; more research needed for better treatments.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Targeting colon cancer stem cells might lead to better treatment results.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Minoxidil sulfate stimulates hair growth.

Humans lost body hair relatively recently in evolution.

Stem cell self-renewal is complex and needs more research for full understanding.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

No treatment fully prevents hair loss from chemotherapy yet.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.