11 citations,
August 2020 in “Diabetes” Testosterone helps human pancreatic cells increase insulin release.
11 citations,
December 2010 in “The Journal of Urology” Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.
11 citations,
April 2016 in “Translational Andrology and Urology” Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.
10 citations,
February 2008 in “International Journal of Andrology” A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.
8 citations,
March 2020 in “Frontiers in Cell and Developmental Biology” Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.
7 citations,
May 2012 in “International Journal of Andrology” The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.
November 2022 in “Scientific Data” The research identified genes and non-coding RNAs in cells that could be affected by testosterone, which may help understand hair loss and prostate cancer.
Testosterone in human pancreas cells boosts insulin production.
Testosterone in our bodies helps increase insulin secretion from the pancreas.
184 citations,
January 2000 in “European Urology” Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.
160 citations,
April 2008 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” DHT in the human prostate is produced through multiple pathways, not just from testosterone.
147 citations,
April 1990 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride safely lowers DHT levels without affecting testosterone.
87 citations,
April 1973 in “Endocrinology” The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.
54 citations,
July 2002 in “Clinical and Experimental Dermatology” DHT, a testosterone byproduct, causes male pattern baldness.
50 citations,
August 1985 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.
37 citations,
January 2015 in “Evidence-based Complementary and Alternative Medicine” An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
31 citations,
September 2009 in “Natural Product Research” Citrullus colocynthis fruit extract may effectively treat testosterone-related hair loss, similar to finasteride.
31 citations,
January 1995 in “The American journal of medicine” Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
27 citations,
February 2017 in “Biomedicine & Pharmacotherapy” White wax and policosanol from white wax effectively reduced hair loss and promoted hair growth in mice better than a known hair growth drug.
25 citations,
November 2015 in “Journal of Ethnopharmacology” Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.
21 citations,
January 2003 in “Skin pharmacology and physiology” Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.
17 citations,
July 2003 in “Metabolism-clinical and Experimental” Women with female-pattern baldness produce more testosterone, but 5a-reductase inhibition treatment won't help.
14 citations,
December 1998 in “The Journal of Clinical Endocrinology and Metabolism” MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.
12 citations,
October 2018 in “Aging male/The aging male” Higher BMI and lower testosterone are linked to more aggressive prostate cancer.
10 citations,
December 2019 in “in Vivo” Testosterone makes the connections in the uterus lining simpler and lowers certain protein levels, which might lead to infertility.
8 citations,
November 2017 in “Saudi Journal of Biological Sciences” A mix of Panax ginseng and bee-pollen may help prevent prostate enlargement in rats.
8 citations,
September 2017 in “Journal of Natural Medicines” Applying an extract from Perilla frutescens helps hair grow and fights the effects of hair loss hormones.
8 citations,
January 1991 in “European Urology” Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.
8 citations,
July 2018 in “Analytical sciences” Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.
6 citations,
May 2022 in “Research and reports in urology” Caesalpinia bonduc seed extracts may help treat enlarged prostate in rats.