research Ingestion of Topical Steroid Triggering Pustular Psoriasis?
Accidentally eating a topical steroid may rarely cause acute generalized pustular psoriasis.
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research Efficacy and Adverse Effects of Corticosteroid Pulse Therapy in Alopecia Areata
Pulse corticosteroids help regrow hair in alopecia areata but have side effects, especially betamethasone.
research Sulfur Treatment for Scabiosis in Local Puppy
Sulfur-based treatments combined with simparica effectively treat scabies in puppies.
research Protein Kinase C Downregulation Upon Rapamycin Treatment Attenuates Neuroinflammation and Mitochondrial Disease
Rapamycin treatment helps reduce brain inflammation and symptoms of mitochondrial disease by blocking specific pathways in mice.
research Food Hypersensitivity-Induced Chronic Gastrointestinal Inflammation in a Non-Human Primate Model of Diet-Induced Obesity
A high-fat diet caused severe health problems in female macaques but was reversible with a normal diet, while male macaques reacted differently.
research Primary Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor
Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.
research Veterinary Pharmacology
Some plant extracts may treat livestock diseases, certain animal treatments are safe and effective, but more research on drug safety and resistance is needed.
research Effects of Parthenolide on Androgenetic Alopecia in Mice and Human Follicle Dermal Papilla Cells
Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.
research The Role of Tofacitinib in the Management of Alopecia Totalis
Tofacitinib helped regrow hair in a patient with severe hair loss and improved their quality of life without side effects.
research Skeletal Site-Dependent Expression of the Androgen Receptor in Human Osteoblastic Cell Populations
Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.
research Impaired Wound Healing in Transgenic Mice Overexpressing the Activin Antagonist Follistatin in the Epidermis
Overexpressing follistatin in mice delays wound healing and reduces scar size.
research Improved Health-Span and Lifespan in mtDNA Mutator Mice Treated with the Mitochondrially Targeted Antioxidant SkQ1
SkQ1 antioxidant improved health and lifespan in mice.
research Long-Term Bezafibrate Treatment Improves Skin and Spleen Phenotypes of the mtDNA Mutator Mouse
Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.
research Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands
Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
research Premature Graying, Balding, And Low Bone Mineral Density In Older Women And Men
Balding men had lower bone density, while balding women had higher hip bone density.
research Parameters of Obesity in Polycystic Ovary Syndrome
Obesity is common in PCOS patients and early treatment is important for their heart and metabolic health.
research Alopecia Areata Treated with Phenolization and Intravenous Dexamethasone Pulses
The treatment using phenol and dexamethasone was effective for alopecia areata with no recurrence in 6 months.
research From Evidence to Practice: Insights from the Multidisciplinary Team on the Optimal Integration of GLP-1 Receptor Agonists in Obesity Management Services
GLP-1 receptor agonists help with weight loss but need to be combined with other treatments for best results.
research The Impact of Gender Affirming Hormone Therapy on Physical Performance
Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.
research The Influence of ESR1 Polymorphisms on Hormonal, Metabolic, and Mineral Balance Markers in Women with Hyperandrogenism
Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.
research Changes in Bone Mineral Density in Women with Early-Onset Androgenetic Alopecia and Their Correlations with Hair-Loss Stages: A Cross-Sectional Study
Women with early-onset baldness should be checked for early bone loss, but bone density doesn't change with baldness severity.
research Polycystic Ovary Syndrome: Early Detection in Adolescents
Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.