Alopecia Areata Treated with Phenolization and Intravenous Dexamethasone Pulses

January 2013 in “ International journal of trichology ”

Sumit Kar, Neha Singh

alopecia areata phenol intravenous dexamethasone dexamethasone pulse therapy alopecia dexamethasone

Studysummary The researchers reported a case of a young girl with alopecia areata who responded well to a combination therapy of 88% phenol and dexamethasone, with no recurrence observed during six months of follow-up. Our plain-language summary of this paper — not a Tressless recommendation.

A 13-year-old girl with extensive alopecia areata, affecting over 50% of her scalp, was treated with a combination of 88% phenol and intravenous dexamethasone pulses. She underwent 5 sessions of phenolisation and 4 monthly dexamethasone pulses over 4 months. The treatment resulted in significant hair regrowth with no recurrence after 6 months of follow-up. The study highlighted the effectiveness of combining phenol and dexamethasone for rapid and improved outcomes in treating alopecia areata, with no reported side effects in this case.

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research Pulsed Administration of Corticosteroids in the Treatment of Alopecia Areata

117 citations , February 1996 in “International Journal of Dermatology”

This study found that monthly oral prednisolone pulses of 300 mg were effective and safe for treating widespread alopecia areata, with 58.3% of patients achieving cosmetically acceptable hair growth.