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VDR regulation varies by tissue and is crucial for its biological functions.

The conclusion is that Darier-White disease was accurately described by White but he missed the key feature of dyskeratotic cells which Darier identified.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by blocking male sex hormones.

Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.

People with myotonic dystrophy type 1 have a higher chance of getting skin tumors, including melanoma.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

The conclusion is that primary scarring alopecia is a complex condition that requires early and accurate diagnosis for effective treatment.

A woman with multiple autoimmune diseases showed improvement in hair loss but not in skin discoloration after treatment.

Zinc supplements improved hair and skin conditions in two patients.

Skin organ culture helps us understand skin biology and diseases better.

Various potential triggers may be causing the rise in frontal fibrosing alopecia, and avoiding these could help stop the disease's increase.

Dermatologists found teledermatology useful and confidence-boosting for diagnosing skin conditions, but faced limitations like technical issues and prescription restrictions. Despite this, they saw its potential to improve access to skin care, especially in remote areas.

A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.

Platelet-rich plasma shows potential for hair loss and skin rejuvenation but needs more research for widespread use.

Silencing certain circadian clock genes increases skin pigmentation.

Cyclosporine cleared a woman's resistant skin condition quickly and kept it away for over a year.

A baby with a rare metabolic disorder developed a rash not cured by zinc alone, likely due to both zinc and amino acid deficiencies.

Vitamin D is important for skin health and can affect various skin diseases.

Hair gets thinner and grayer with age, and density decreases more in men on top and in women on top and back.

A man had an allergic reaction to minoxidil, which stopped after he discontinued use and started corticosteroids.

No strong genetic link to other skin conditions was found, but some genetic factors may make people more likely to get seborrheic dermatitis.

Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.

Niosomes are a promising and effective way to deliver drugs through the skin.

Graham-Little syndrome causes scarring hair loss and skin bumps.

A woman developed white patches on her skin and curly hair after hepatitis C treatment, likely due to the medication interferon alpha.

There is a significant need for better-validated quality of life tools in dermatology.

Reflectance confocal microscopy reliably identifies skin cancer features like horizontal skin tissue sections.

PRP shows promise for skin rejuvenation but needs more research.

Proper skin toxicity management in chemotherapy is key to continuing treatment and keeping patient quality of life high.