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Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Human skin can make serotonin and melatonin.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

New micelle solutions greatly improve skin delivery of certain antifungal drugs.

Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

The document concludes that proper diagnosis and a combination of medical, hair-care, and surgical treatments are important for managing alopecia in black women.

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.