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Coats' Plus is a genetic disorder with eye abnormalities, brain calcification, poor growth, bone and skin issues, and movement disorders.

Excessive selenium from a supplement caused toxicity but patients recovered with care.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Finasteride helps reduce heart issues and improves heart function.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Hormonal therapies are safe and effective for treating adult women's acne.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Women with excessive male-pattern hair growth should get a full hormone check-up to find and treat any underlying issues, considering both medical and emotional aspects.

Activin activation in skin cells speeds up wound healing without affecting scar quality.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.