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Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.

Certain drugs that block specific enzymes can help treat prostate diseases.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Indigenous herbal medicines in the Indian subcontinent have potential for drug development but need more research and standardization.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

More research is needed to understand how testosterone is maintained in adult males.

Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.

Treating both the mind and skin together, especially by managing stress, can greatly improve outcomes for skin disorders linked to psychological issues.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

Scientists found new genetic areas that affect how rice root hairs grow and develop.

Fusarium sp. strain K-23 helps Arabidopsis plants grow better in salty soil by promoting root hair growth.

Certain genetic variants are linked to frontal fibrosing alopecia in Spanish patients.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

5-Aminolevulinic acid can help chicken sperm move better at the right amount.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

The dog's skin condition improved significantly after seven days of treatment.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

A new mutation in the CYP11B1 gene was found in a woman with mild hyperandrogenemia, a rare cause of non-classic congenital adrenal hyperplasia.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

The document concludes that validated methods are needed to ensure the quality of fluconazole drugs and that new antifungal medications are necessary due to safety and resistance concerns.