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The authors suggest that 5-α-reductase inhibitors, like dutasteride, are effective in treating frontal fibrosing alopecia and should be the first-line treatment, with other options for severe cases. They also recommend further research on Janus kinase inhibitors.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Trilostane may help delay epilepsy development by increasing certain brain chemicals.

Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.

More research is needed to understand how testosterone is maintained in adult males.

Minoxidil lowers blood pressure and spreads throughout the body in normal rats.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Using A132 hair dye with sunlight can cause skin damage and hair loss.

A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

Micelles can change cetirizine's ionization, affecting its effectiveness in treatments.

Infrared radiation can cause skin aging and cancer at high temperatures but may have therapeutic benefits at controlled levels.

PCOS is a condition causing irregular periods, excess male hormones, and infertility, often managed by targeting insulin resistance and specific symptoms.

Methylene blue is less effective than normal saline solution for storing hair grafts and may reduce graft survival.

Copper deficiency may cause hair loss, and treating it could involve nutrition and hormones.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Certain genetic variants are linked to frontal fibrosing alopecia in Spanish patients.

Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

A new mutation in the CYP11B1 gene was found in a woman with mild hyperandrogenemia, a rare cause of non-classic congenital adrenal hyperplasia.

The document concludes that there are various causes and treatments for hair loss, with hair transplantation being a notable option.

Minoxidil, finasteride, and hair transplantation combined give best results for hair loss.

Minoxidil, finasteride, and hair transplantation combined give best results for hair loss.

The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.

Light therapy on the brain shows promise for treating brain diseases and improving brain function.