1 citations,
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” Hair can't be reliably repaired once damaged; prevention and proper product use are key to maintaining hair health.
176 citations,
January 2003 in “Journal of Investigative Dermatology” Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
117 citations,
November 2006 in “Experimental Dermatology” The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
68 citations,
May 2018 in “PLOS Biology” Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.
65 citations,
July 2006 in “Journal of biological chemistry/The Journal of biological chemistry” The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.
61 citations,
September 2010 in “Genomics” The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
56 citations,
February 2010 in “PLOS ONE” Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
52 citations,
October 2012 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
48 citations,
May 2015 in “NPJ microgravity” A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.
43 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” The article concludes that advancements in hair cosmetics require dermatologists to stay informed about products and their potential risks, including allergies and higher risks for hairdressers.
40 citations,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
30 citations,
July 2010 in “Experimental Dermatology” Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.
25 citations,
September 2018 in “Molecular Biology of the Cell” Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
19 citations,
September 2014 in “British Journal of Dermatology” Minoxidil foam 5% effectively treats hair loss in both frontal and vertex scalp regions.
19 citations,
January 2009 in “International review of cell and molecular biology” Hair's strength and flexibility come from its protein structure and molecular interactions.
18 citations,
August 2018 in “The FASEB journal” Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.
13 citations,
December 2018 in “Development, Growth & Differentiation” Sex hormones, especially estradiol, can change chicken feather shapes and colors.
12 citations,
June 2017 in “Cell Cycle” Minoxidil foam helps hair growth by increasing good proteins and decreasing bad pathways in men with hair loss.
8 citations,
June 2012 in “PloS one” Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.
4 citations,
January 2020 in “Frontiers in Physiology” Good feather growth in poultry needs the right balance of proteins, amino acids, minerals, and vitamins.
1 citations,
February 2009 in “Journal of Investigative Dermatology” Lipase H is important for hair follicle function and shaping hair fibers.
1 citations,
February 2009 in “Journal of Investigative Dermatology” VEGF helps squamous cell carcinoma grow in ways beyond just blood vessel formation.
May 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” KAP-depleted hair causes less immune response and is more biocompatible for implants.
Hair keratin treatments can be harmful, potentially causing health issues like skin reactions and cancer.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
Chrysanthemum zawadskii extract may help treat hair loss by promoting hair growth and affecting growth factors.
48 citations,
November 2002 in “Journal of biological chemistry/The Journal of biological chemistry” Genetic variations in hair keratin proteins exist but don't significantly affect hair structure.
6 citations,
April 2005 in “Journal of dermatological science” The study found nine new hair protein genes in human hair follicles.
April 2024 in “Advances in Redox Research” Human hair strength and health are linked to sulfur compounds that can be reduced by stress but improved with sulfur supplements.
16 citations,
November 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.