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Early-onset baldness is linked to a higher risk of aggressive prostate cancer in African-American men, especially before age 60.

The model and estimator can predict drug exposure in kidney transplant patients well.

Food intake, not genetics, affects how the body processes tadalafil and finasteride.

The severity of symptoms in nonclassical congenital adrenal hyperplasia is not determined by CYP21A2 gene variations.

Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.

Some drugs can cause serious side effects like heart issues and nervous system problems, but certain drugs for Parkinson's and overactive bladder may be safer, though they still have some common side effects.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

A woman developed Cushing syndrome and adrenal insufficiency from using fluticasone and ritonavir together.

Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Repurposing existing drugs for COVID-19 shows promise but requires more research to confirm effectiveness.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Finasteride doesn't affect omeprazole metabolism in Japanese people.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Voriconazole can cause serious side effects, especially in long-term use.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

Pharmaceutical care in transplantation faces challenges but has promising future opportunities for better outcomes.

Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.