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Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Women with conditions like PCOS may have a higher risk of COVID-19, but treatments like isotretinoin could help those with acne.

Decreasing MIG6 can increase the movement and invasiveness of MEK-inhibited mutant NRAS melanoma, particularly when stimulated by EGF.

High levels of androgens can cause skin issues like acne, hair loss, and excessive hair growth.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

Vitamin D is important for skin health and can help treat and prevent various skin conditions.

The document concludes that antiandrogenic drugs like cyproterone acetate and spironolactone are effective but not permanent treatments for skin-related androgenization in women.

CYLD deficiency in skin tumors disrupts hair follicle cell processes and protein secretion.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Naked mole-rats have unique skin and hair nerve structures, lacking certain pain and temperature-related neuropeptides.

P2X₃-IR fibers are widespread in rat skin and likely help detect pain.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.

FLRG and follistatin have different roles in wound healing.

Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

Biologic treatments for Crohn's disease and ulcerative colitis can cause skin problems, and doctors should adjust treatment if these occur.

The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.

Gene therapy shows promise for improving wound healing, but more research is needed for human use.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Alopecia areata patients have higher levels of certain immune receptors, suggesting new treatment possibilities.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Targeted cancer therapies often cause serious skin problems that need careful management.

New effective scar treatments are urgently needed due to the current options' limited success.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.