research Association of Estrogen Receptor Gene Variants (ESR1 and ESR2) with Polycystic Ovary Syndrome in Tunisia
Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.
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research Polycystic Ovary Syndrome: A Comprehensive Review
The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.
research A Machine Learning and Network Framework to Discover New Indications for Small Molecules
A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.
research Altered Methylation Pattern of the SRD5A2 Gene in the Cerebrospinal Fluid of Post-Finasteride Patients: A Pilot Study
Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.
research Characterization of Follicular Minoxidil Sulfotransferase Activity in a Cohort of Pattern Hair Loss Patients from the Indian Subcontinent
About 41% of Indian hair loss patients have low enzyme activity that affects hair loss treatment effectiveness, with men affected more than women. Testing for this can guide treatment.
research Effect of Finasteride Particle Size Reduction on Its Pharmacokinetic, Tissue Distribution, and Cellular Permeation
Smaller finasteride particles increase effectiveness in treating hair loss.
research Finasteride Treatment and Male Breast Cancer: A Register-Based Cohort Study in Four Nordic Countries
Finasteride use may increase the risk of male breast cancer.
research Variations in Alanine Aminotransferase Levels Within the Normal Range Predict Metabolic and Androgenic Phenotypes in Women of Reproductive Age
Normal-range ALT levels can indicate metabolic and hormonal imbalances in young women.
research Effect of Phlebotomy Versus Oral Contraceptives Containing Cyproterone Acetate on Clinical and Biochemical Parameters in Women with Polycystic Ovary Syndrome: A Randomized Controlled Trial
Blood removal and birth control pills both helped with hormone levels in women with PCOS, but birth control was better for regular periods and blood removal had fewer side effects.
research Temperament and Character Differences of Patients with Polycystic Ovary Syndrome
People with polycystic ovary syndrome (PCOS) are more likely to have higher levels of depression and anxiety, but their personality traits are similar to those without PCOS.
research A Case Report of Thrombotic Thrombocytopenic Purpura Associated with Systemic Lupus Erythematosus: Overlapping Features
Early diagnosis, intensive therapy, and careful follow-up are crucial for managing overlapping TTP and SLE.
research Relation of Urinary Stone Disease with Androgenetic Alopecia and Serum Testosterone Levels
Balding and low testosterone increase risk of urinary stones.
research Bald Thigh Syndrome in Sighthounds: Revisiting the Cause of a Well-Known Disease
Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.
research Close Correlation Between Hyperandrogenism and Insulin Resistance in Women With Polycystic Ovary Syndrome Based on Liquid Chromatography With Tandem Mass Spectrometry Measurements
Women with PCOS who have high male hormone levels often also have insulin resistance.
research Integrated Transcriptomics and Metabolomics Analyses of Stress-Induced Murine Hair Follicle Growth Inhibition
Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.
research Transcriptome Analysis of Improved Wool Production in Skin-Specific Transgenic Sheep Overexpressing Ovine β-Catenin
Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.
research Estrogen Modulates Mesenchymal-Epidermal Interactions in the Adult Nipple
Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
research Role of Plasminogen Activator Inhibitor Type 1 (PAI-1) in PCOS Patients
People with PCOS have higher levels of PAI-1, which may increase their risk of heart disease and fertility issues.
research Scalp Hair Sweating as a Predictor of Hair Cortisol Level in Humans Compared to Obesity and Other Confounders
Scalp hair sweating is a significant predictor of hair cortisol levels.
research Donor Site of Follicular Unit Excision Hair Transplantation: The Relationship Between Appearance and Actual Hair Density, and Hair Diameter
Good-looking donor sites for hair transplants usually have higher hair density and thicker hair.
research Reduced Levels of Serum 25-Hydroxyvitamin D in Alopecia Areata: A Systematic Review and Meta-Analysis
People with alopecia areata often have lower vitamin D levels than healthy people.
research Change in Prostate-Specific Antigen Concentration in Men with Prostate-Specific Antigen Less Than 2.5 ng/mL Taking Low-Dose Finasteride or Dutasteride for Male Androgenetic Alopecia
Low-dose finasteride and dutasteride reduce PSA levels by 27.8% in men with male androgenetic alopecia.
research The Burden of Disease in Alopecia Areata: Canadian Online Survey of Patients and Caregivers
Alopecia Areata greatly affects the quality of life and mental health of Canadian patients and their caregivers.
research Comprehensive Transcriptome Profiling Between Balding and Non-Balding Scalp of Female Pattern Hair Loss in Asian
SFRP2 and PTGDS may be key factors in female hair loss.
research Management of Polycystic Ovarian Syndrome: Looking Beyond the Ovaries
PCOS treatment focuses on lifestyle changes and specific medications to manage symptoms and complications.
research Attention to Innate Circadian Rhythm and the Impact of Its Disruption on Diabetes
Disrupting natural body clocks increases the risk of developing type 2 diabetes.
research Evaluating the Role of Thyroid Stimulating Hormone and Ferritin Levels with Hair Loss Among Patients with COVID-19: Case-Control Study
Thyroid function may influence hair loss after COVID-19.
research Natural Product Shi-Bi-Man Regulates Lactic Acid Metabolism and Drives Hair Follicle Stem Cell Activation to Promote Hair Regeneration
Shi-Bi-Man activates hair follicle stem cells and promotes hair growth by changing lactic acid metabolism and other cellular processes.
research Discovering the Potential of Natural Remedies in Post COVID-19 Complications Based on In Silico Techniques
Natural compounds, especially Withaferin-A, may help treat post-COVID-19 complications, but some may have side effects.
research Calcineurin-Based Immunosuppression in Renal Transplantation: Focus on Efficacy, the Role of Steroids, and Cardiovascular Risk
Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.