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In vivo confocal scanning laser microscopy is an effective, non-invasive way to study and measure new hair growth after skin injury in mice.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Black dots under trichoscopy can appear in different hair and scalp conditions, not just in alopecia areata.

Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.

Ethosomal minoxidil improves hair growth by penetrating deeper into skin and shortening hair cycle.

Mice without the IL-6 gene had more hair growth after injury due to higher activity of a related protein, Stat3.

New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

Ethosomes are a promising way to deliver drugs through the skin.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

TrichoScan is reliable for counting and measuring hair density but may not accurately assess hair types in women with hair loss.

In vivo reflectance confocal microscopy is useful for evaluating hair shaft diseases but needs improvement for deeper hair follicle issues.

The conclusion is that the IL-6/STAT3 activation affects p63 expression in healing wounds, which may help in hair follicle regeneration.

Careful selection of mice by genetics and age, and controlled housing conditions improve the reliability of hair regrowth in wound healing tests.

After skin is damaged, noncoding dsRNA helps prostaglandins and Wnts work together to repair tissue and promote hair growth.

White blood cells and their traps can slow down the process of new hair growth after a wound.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

The skin's microbiome helps hair regrow by boosting certain cell signals and metabolism.

The treatment improved hair growth and reduced hair loss.