research Tactile Innervation Densities Across the Whole Body
The skin has about 230,000 touch-sensitive nerve fibers, with high concentrations in the hands and face.
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research Tactile Innervation Densities Across the Whole Body
Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.
research Three-Dimensional Reconstructions of Mechanosensory End Organs Suggest a Unifying Mechanism Underlying Dynamic, Light Touch
Dynamic, light touch is sensed through a common mechanism involving Piezo2 channels in sensory axons.
research The Transcriptional Regulator Prdm1 Is Essential for the Early Development of the Sensory Whisker Follicle and Is Linked to the Beta-Catenin First Dermal Signal
Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.
research Potential Factors Contributing to Androgenetic Alopecia
Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.
research The Role of Interface Geometry and Appendages on the Mesoscale Mechanics of the Skin
Skin's uneven surface and hair follicles affect its stress and strain but don't change its overall strength, and help prevent the skin from peeling apart.
research Hair Cortisol in Sheltered Cows and Its Association with Other Welfare Indicators
High hair cortisol levels indicate stress in cows due to poor shelter conditions and health issues.
research Targeted Expression of SV40 T Antigen in the Hair Follicle of Transgenic Mice Produces an Aberrant Hair Phenotype
SV40 T antigen in hair follicles causes abnormal hair and health issues in mice.
research Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth
Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
research Menstrual Disorders in Adolescents
The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.
research Role of Insulin Resistance and Diet in Acne
Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
research Obesity, Polycystic Ovarian Syndrome, and Thyroid Dysfunction in Women with Epilepsy
Women with epilepsy on certain medications might gain weight and have higher thyroid-stimulating hormone levels, but not more polycystic ovarian syndrome.
research Anorexia Nervosa and Bulimia Nervosa: Analysis of Prevalence, Mortality, Outcomes, and Endocrine Changes
Anorexia Nervosa and Bulimia Nervosa are complex eating disorders with increasing incidence among young females, significant morbidity, and varying mortality rates, requiring more research for better treatment.
research Recent Advances in Neuropeptide-Related Omics and Gene Editing: Spotlight on NPY and Somatostatin and Their Roles in Growth and Food Intake of Fish
New tools show that in fish, NPY increases feeding and somatostatin decreases it.
research Acidic and Basic Hair/Nail (Hard) Keratins: Their Colocalization in Upper Cortical and Cuticle Cells of the Human Hair Follicle and Their Relationship to Soft Keratins
Hair and nail cells share similar proteins, indicating a common differentiation pathway.
research Cortical Cell Types and Intermediate Filament Arrangements Correlate with Fiber Curvature in Japanese Human Hair
Hair curvature in Japanese people is linked to specific cell types and filament arrangements in the hair cortex.
research An Opportunity Missed: Managing an Aggressive Adrenal Cortical Carcinoma
The case shows the importance of quick and thorough evaluation of adrenal tumors to prevent rapid disease progression and poor outcomes.
research Stiffness of Human Hair Correlates with the Fractions of Cortical Cell Types
Hair stiffness is higher when it has more para-like cortical cells.
research Hyperandrogenism in a Postmenopausal Woman: A Rare Case of Ectopic Adrenal Cortical Gland
A postmenopausal woman's excess male hormone symptoms were caused by a rare adrenal gland tissue in her ovary.
research A Pure Androgen-Secreting Adrenal Cortical Tumor in a 13-Year-Old Female
A 13-year-old girl's masculine symptoms improved after surgery for a rare adrenal tumor that produced male hormones.
research Frontotemporal Dementia with Parkinsonism Presenting as Posterior Cortical Atrophy
A woman's unique dementia was misdiagnosed, a genetic mutation increases Parkinson's risk with age, and finasteride may help with Tourette syndrome.
research Treatment-Resistant Schizophrenia and Global Cortical Atrophy in a Patient with Turner Syndrome
A person with Turner Syndrome showed severe schizophrenia that didn't respond to treatment and had brain shrinkage.
research Minoxidil Regulates Aging-Like Phenotypes in Rat Cortical Astrocytes In Vitro
Minoxidil may help reduce aging effects in brain cells.
research DKK1 Mediated Inhibition of Wnt Signaling in Postnatal Mice Leads to Loss of TEC Progenitors and Thymic Degeneration
Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
research The Ophthalmological Complications of Targeted Agents in Cancer Therapy: What Do We Need to Know as Ophthalmologists?
Cancer treatments can cause various eye problems, so eye doctors should know how to diagnose and treat these early.
research Characterization and Expression Analysis of KAP7.1 and KAP8.2 Genes in Liaoning New-Breeding Cashmere Goat Hair Follicles
KAP7.1 and KAP8.2 genes are crucial for cashmere quality in goats.
research Gene Expression of Mouse S100A3, a Cysteine-Rich Calcium-Binding Protein, in Developing Hair Follicle
S100A3 protein is crucial for hair shaft formation in mice.
research Curly Wood and Tiger Tails: The Tiger Tail Phenomenon in Trichothiodystrophy
Tiger tail bands in hair are caused by wavy hair fibers with melanin, unlike straight fibers in normal hair.
research Fractography of Human Hair
Moisture content significantly affects how human hair breaks.
research Cuticle Damage and the Tensile Properties of Human Hair
Cuticle damage doesn't affect hair's tensile strength; the cortex is responsible for it.