This study found that hair cortisol concentrations in mother-daughter pairs are a potential biomarker for cortisol responses to chronic stress, with daughter-mother similarities affected by parenting styles and children's symptoms.
March 2014 in “Journal of The American Academy of Dermatology” Cortexolone 17a-propionate may be an effective new treatment for hair loss.
May 2012 in “Neurotoxicology and Teratology” Hair cortisol can be a reliable way to measure long-term stress.
April 2012 in “Journal of the American Academy of Dermatology” Clofazimine may be effective for treating ashy dermatosis.
January 2012 in “CINECA IRIS Institutial Research Information System (University of Genoa)” This study observed fluctuations in hair cortisol levels in rabbits, indicating their HPA axis activity responded similarly to surgical and environmental stressors, suggesting potential anthropomorphic evaluations of stress.
April 2011 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Hair cortisol is a reliable long-term stress marker during pregnancy.
October 2008 in “Experimental and Clinical Endocrinology & Diabetes” This study found that unemployed individuals had higher hair cortisol content over a 6-month period, indicating greater cumulative cortisol exposure compared to employed individuals.
January 2008 in “Zhonghua linchuang mianyi he biantai fanying zazhi” This study found that treatment with Shunyou dispersible tablet and prednisone improved clinical symptoms in patients with lupus nephritis, showing significant benefits over time along with a good safety profile.
August 1993 in “Journal of Dermatological Science” Cyclosporin and minoxidil promote hair growth.
January 2022 in “Clinical, Cosmetic and Investigational Dermatology” This study reports promising results for alopecia universalis treatment using a combination of systemic methotrexate and low-dose corticosteroids with topical minoxidil, though monitoring for side effects is necessary.
August 2021 in “Asian Journal of Pharmaceutical and Clinical Research” In this randomized trial, a solid shampoo formulated with plant extracts was more effective than placebo in improving androgenetic alopecia and reducing hair cortisol and DHT concentrations in men.
407 citations
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January 2008 in “Cochrane Database of Systematic Reviews” This review found that glucocorticoid corticosteroids can improve muscle strength and function in boys with Duchenne muscular dystrophy in the short term, but they are associated with significant short-term adverse effects.
118 citations
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October 2014 in “Journal of Dairy Science” This study found that in lactating Holstein cows, hair from the tail switch, which grows faster and is more sensitive to cortisol changes, is ideal for measuring hair cortisol levels.
109 citations
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June 2000 in “Development” This study reports that activating Notch signaling in the hair follicle cortex of transgenic mice caused abnormal differentiation of the medulla and cuticle, highlighting potential cell-cell interactions.
97 citations
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January 2006 in “Dermatology” This study found that intramuscular triamcinolone acetonide or pulse therapy effectively treats alopecia areata with manageable side effects, but further strategies are needed to reduce relapse rates.
51 citations
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November 2005 in “Journal of Medical Primatology” This study observed that hair loss in captive rhesus macaques varies with season, sex, and housing conditions, and is significantly correlated with HPA axis activity as indicated by faecal cortisol metabolites.
51 citations
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January 2001 in “Biological & Pharmaceutical Bulletin” This study found that the aqueous ethanol extract of Myricae Cortex demonstrated in vitro testosterone 5alpha-reductase inhibitory activity and in vivo anti-androgenic effects in mouse and hamster models.
43 citations
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August 2016 in “Scientific Reports” This animal study found that Cinnamomi cortex water extract reduced prostate weight and improved histological changes in a benign prostatic hyperplasia model, suggesting potential as a treatment.
38 citations
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September 2013 in “Therapeutic Drug Monitoring” This study found that increased hair cortisol levels among WIFN volunteers suggest higher chronic stress compared to those from a non-First Nation community, possibly linked to socioeconomic factors and poorer health.
38 citations
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January 2013 in “Dermatology” This study found that intravenous high-dose pulse corticosteroids resulted in a complete response in 38% of children with alopecia areata, but the majority of responders relapsed within a year.
35 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This study found that intralesional triamcinolone acetonide is effective for treating localized patchy alopecia areata, with dermoscopy aiding in early detection of clinical response and adverse effects.
31 citations
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April 2016 in “Journal of the American Academy of Dermatology” Oral dexamethasone may help regrow hair in adults with alopecia totalis and universalis.
30 citations
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July 2016 in “Psychoneuroendocrinology” 30 citations
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August 1998 in “International Journal of Dermatology” This study found that systemic corticosteroids led to satisfactory hair regrowth in 38.9% of severe alopecia areata patients, but hair fall occurred upon therapy discontinuation or tapering.
28 citations
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July 2015 in “Dermatologic therapy” This study found that combining topical and oral pulse corticosteroid therapy for severe alopecia areata in children led to long-lasting hair regrowth, especially in AA plurifocalis, with no serious side effects reported.
24 citations
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January 2019 in “Hormone Research in Paediatrics” This study found that gender, puberty, and BMI significantly affect hair cortisol concentrations in children, suggesting these factors should be considered in future research.
24 citations
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February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers identified two new keratin-associated proteins, hKAP1.6 and hKAP1.7, in human hair follicles, contributing to understanding hair fiber differentiation.
23 citations
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August 2017 in “Scientific Reports” Darker hair may lead to higher cortisol readings, suggesting a need to adjust for hair color in studies.
22 citations
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May 2019 in “Animals” In this study, researchers found that high hair cortisol levels, indicating stress in cows, were associated with certain shelter and cow-level conditions such as unclean environments and physical injuries.
21 citations
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January 2017 in “MethodsX” This study found that methanol is more effective than isopropanol at removing external cortisol from grizzly bear hair and suggests that the choice of solvent can influence hair cortisol concentration results.