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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

Finasteride can slow hair loss and promote growth in postmenopausal women.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Both mouse and rat models are effective for testing alopecia areata treatments.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Finasteride helps reduce heart issues and improves heart function.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

Prolactin slows down hair growth in mice.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.