This review highlights that recent advancements in diagnostics and therapies, including AI-enhanced imaging, biomarker analysis, and novel treatments like low-dose oral minoxidil and JAK inhibitors, are improving the precision and customization of hair loss management.
97 citations
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December 2021 in “Cells” This review outlines key considerations for designing fluorescence microscopy experiments in cell biology, discussing the importance of hardware availability, suitability of biological models, and imaging agents to achieve high-resolution and informative images.
26 citations
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November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” TrichoScan effectively measures hair growth improvements in people using minoxidil.
October 2024 in “BMC Genomics” This study examined the cytodifferentiation stage of hair follicle development in cashmere goats, identifying nine cell populations and key regulatory pathways, including transcription factors and keratin genes, that may influence fiber quality and inform breeding strategies.
This study found that applying transfer learning with CNN architectures like AlexNet, VGG16, and ResNet50 achieved 99% accuracy in classifying multiclass hair disorders, suggesting a potential technological aid for dermatologists in diagnosing and treating hair conditions.
12 citations
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August 2015 in “Plastic Surgery” This study found that botulinum toxin type A significantly reduced skin flap necrosis in rats exposed to cigarette smoke, suggesting it may help improve flap viability in smokers.
February 2025 in “PubMed” This study evaluated an AI-driven system for personalizing non-medicated hair loss treatments in women, showing significant improvements in hair growth, shedding, texture, and scalp health over 24 weeks, with no adverse effects reported.
180 citations
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February 2023 in “Journal of Chemical Information and Modeling” In this paper, Chemistry42—a software integrating AI with computational and medicinal chemistry—demonstrated efficiency in designing novel molecular structures targeting DDR1 and CDK20, with properties validated in both in vitro and in vivo studies.
In this study, researchers developed a method for high-resolution live imaging of leg regeneration in the crustacean Parhyale hawaiensis, which effectively captures the entire process at cellular resolution over 10 days while minimizing photodamage.
In this study, a machine-learning model was evaluated for its ability to categorize various hair conditions, achieving high accuracy and balance between precision and recall, with an overall accuracy of 97% in detecting hair problems.
7 citations
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June 2015 in “EMBO Reports” This article discusses how DNA-based phenotyping is used by police to create visual profiles of suspects from crime scene samples, but reports no new research findings.
4 citations
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October 2022 in “Journal of Imaging” This study reported that a new deep learning algorithm using Mask R-CNN improved hair follicle classification accuracy by 4 to 15%, suggesting potential clinical application for enhanced hair loss diagnosis.
2 citations
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July 2024 in “International Journal of Cosmetic Science” In this study, researchers found that differences between self-ratings and assessor ratings of facial appearance vary by age and ethnicity, and these discrepancies, along with assessor ratings of skin features, are predictive of menopausal status across ethnic groups.
January 2014 in “cIRcle (University of British Columbia)” This research found that modifying brachytherapy seeds with contrast-enhancing materials in photoacoustic imaging increased signal-to-noise ratios and imaging depth, and demonstrated potential for tissue differentiation by analyzing temperature-induced changes in PA intensity.
January 2014 in “Anales Médicos de la Asociación Médica del Centro Médico ABC” This study suggests that a combination of topical minoxidil with oral finasteride or dutasteride promotes hair growth in treating androgenetic alopecia, with only minor safety concerns reported.
22 citations
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April 2023 in “The Journal of Cell Biology” In this study, researchers found that coordinated intercellular Ca2+ signaling among basal stem cells in mice is crucial for cell cycle progression and tissue-wide communication during epidermal regeneration.
This study validated a new test method using a patented chamber to measure the efficacy of a sunscreen in reducing carbon black particle adhesion, with a 55% reduction observed on treated skin in a group of 22 women.
January 2025 in “Diagnostics” This study found that a new three-dimensional high-frequency ultrasound (3D-HFUS) can successfully visualize skin tumors and inflammatory hair diseases, offering promising noninvasive diagnostic and evaluation capabilities compared to traditional two-dimensional methods.
June 2026 in “Journal of Clinical Medicine” This study reported that a single-session scalp procedure combining several components, including PRP and botulinum toxin, was associated with significant improvements in hair thickness and reduced vellus hair proportion in androgenetic alopecia patients, although further controlled trials are needed to establish causation.
21 citations
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May 2024 in “American Journal of Medical Genetics Part A” This study observed that among patients with Myhre syndrome, those with the SMAD4 gene variant p.Arg496Cys experienced fewer symptoms like hearing loss, while those with the p.Ile500Thr variant often had severe aortic hypoplasia, highlighting the diverse symptom progression and genetic factors of this rare condition.
March 2026 in “The Open Dentistry Journal” This study found significant gender-based differences in forehead dimensions among 297 participants, with males showing larger vertical measurements, which could inform applications in forensic identification, cosmetic surgery, and anthropological research.
In this study, researchers observed a high degree of plasticity in somatosensory axons innervating Merkel cells in adult mouse skin, revealing that both epithelial-neural crosstalk and intrinsic neural mechanisms contribute to axonal patterning and remodeling during epithelial homeostasis.
January 2023 in “Journal of clinical pharmacy and therapeutics” This study found that isoliensinine, a natural compound identified from a database, effectively prevented stress-induced hair greying in mice by blocking β-2 adrenergic receptors on melanocyte stem cells in hair follicles.
February 2021 in “Journal of Investigative Dermatology” This study found that specific junctional proteins are significantly downregulated in balding regions of the scalp in men with androgenetic alopecia, suggesting disrupted cell communication may play a role in hair loss.
822 citations
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January 2021 in “Genome biology” This study presents a new method called scMC that effectively distinguishes biological from technical variation in single-cell genomics datasets, demonstrating its ability to accurately align and detect biological signals across various experiments.
3 citations
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November 2019 in “Journal of the ASEAN Federation of Endocrine Societies” This case report describes an unusual variant of Turner Syndrome in a 20-year-old female that required comprehensive medical and psychological care, including hormonal therapy that resolved symptoms like alopecia.
January 2025 in “Indian Dermatology Online Journal” This case report highlights an unusual presentation of mycosis fungoides with photo-exacerbated lesions and a rare CD4+/CD8+ immunohistochemical phenotype, complicating diagnosis and treatment.
1 citations
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January 2025 in “IntechOpen eBooks” This source outlines the development of a comprehensive system for evaluating the safety and efficacy of cosmetics in China compared to established practices in Europe and the U.S., highlighting factors like AI technologies and specific product categories such as anti-aging and sun protection.
3 citations
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July 2025 in “Pharmaceutics” In this study, Levant Storax Cream demonstrated the highest wound healing rates in rats compared to a commercial wound care cream, a complex cream, and placebo.
124 citations
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November 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that human peptidylarginine deiminase type III is the predominant isoform in hair follicles and may modulate structural proteins during hair and hair follicle formation.