10 citations
,
April 2013 in “Journal of Investigative Dermatology” This study found that ovine dermal papilla cells exhibit robust aggregation in culture, offering a model to investigate the regulation of hair follicle dermal papilla size.
10 citations
,
November 1997 in “British Journal of Dermatology” This study found that the non-steroidal antiandrogen RU58841 increased hair growth rates and promoted hair cycle initiation in balding human scalp grafts on testosterone-conditioned nude mice, indicating a positive effect on hair growth.
4 citations
,
January 2016 in “Journal of analytical & bioanalytical techniques” This study evaluated a hair growth gel with Hibiscus rosa sinensis, Eclipta alba, and Solanum nigrum extracts, demonstrating consistent homogeneity, 5 α-reductase inhibitory activity, and no skin irritation.
4 citations
,
May 2007 in “Journal of Dispersion Science and Technology” This study found that hinokitiol in cationic vesicles promoted hair growth in mice, potentially due to its high substantivity on the skin.
3 citations
,
April 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, beta-caryophyllene enhanced wound healing in female mice by improving re-epithelialization, cell proliferation, and cell migration, suggesting potential benefits of essential oil compounds in inflammation reduction.
1 citations
,
January 2001 in “Journal of Toxicology-cutaneous and Ocular Toxicology” This review discusses the roles of hair follicles and sebaceous glands in percutaneous transport and reports no new results, noting a lack of adequate models and methodologies.
1 citations
,
January 2017 in “Elsevier eBooks” This article reviews various hair growth and hair loss treatments, noting limited new developments since FDA-approved drugs but highlights recent cosmetic surgery and potential cell-based therapies; it reports no original findings.
December 2025 in “International Journal of Therapeutic Innovation.” This study developed an herbal hair mask using natural ingredients like rice water, aloe vera gel, and coconut oil, which demonstrated moisturizing, strengthening, and protective properties, potentially aiding in maintaining healthy and resilient hair.
December 2025 in “The American Journal of Medical Sciences and Pharmaceutical Research” This study outlines how combined ultrasonic and infrared hair treatments may enhance hair restoration and performance by breaking down keratin disulfide bonds for better treatment access and sealing cuticle scales to preserve improvements, with potential applications in salon and home settings.
January 2025 in “International Journal for Research Trends and Innovation” This study assessed a herbal hair oil made from various plant ingredients, observing it supported hair growth and maintained stability for 45 days, with the phytochemical profile indicating the presence of saponins, sulfur, and ascorbic acid.
January 2025 in “Journal of Pharmacognosy and Phytochemistry” This study developed plant-pigment-based shampoos using extracts from Neem, Fenugreek, Hibiscus, and Butterfly Pea, which demonstrated stability, antimicrobial properties, and potential scalp benefits such as hair growth promotion and dandruff reduction, making them a promising alternative to synthetic dyes.
This study focused on developing a nanoemulsion-based gel for delivering minoxidil, aiming to enhance its contact time with the scalp and potentially improve skin absorption compared to conventional topical solutions.
February 2026 in “PubMed” This study reported that para-phenylenediamine and toluene-2,5-diamine are the main sensitizers in hair dye-related allergic contact dermatitis, with significant cross-reactivity to several other compounds.
April 2024 in “International Research Journal Of Modernization In Engineering Technology And Science” This study identified promising properties of a herbal shampoo formulation, suggesting its potential for human cosmetic use, but notes that further optimization is needed to fully explore its benefits.
February 2023 in “International Journal of Pharmaceutics” In this study, the researchers developed minoxidil cubosomes using nanotechnology, which improved drug penetration in the skin, showed greater hair growth efficacy, and reduced adverse skin reactions compared to traditional minoxidil solutions.
2 citations
,
December 2019 in “Biomedical dermatology” In this study, researchers found that topical ketoconazole showed delayed hair growth compared to minoxidil in female pattern hair loss but had fewer side effects, though patient satisfaction was similar for both treatments.
March 2014 in “Medicina cutánea ibero-latino-americana” This review discusses the role of melatonin in skin and hair physiology, highlighting clinical evidence for its potential benefits in treating androgenetic alopecia, but does not report new results.
October 2025 in “International Journal For Multidisciplinary Research” This review study found strong scientific support for traditional Indian hair care practices, demonstrating that herbs like Amla, Bhringraj, and Ashwagandha have beneficial effects on hair growth and scalp health, backed by technological advancements that enhance their therapeutic potential.
42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” This article discusses the need for rational strategies in developing hair loss drugs targeting specific events in hair follicle cycling, reporting no clinical findings but emphasizing the importance of understanding molecular controls.
40 citations
,
October 2002 in “Endocrinology” In this study, synthetic vitamin D3 analogs stimulated hair growth and formation of normal hair follicles in nude mice, unlike the natural form 1,25 dihydroxyvitamin D3.
39 citations
,
September 2013 in “Journal of Cosmetic Dermatology” This review summarizes causes and treatments of androgenetic alopecia with a focus on herbs as potential alternatives, but reports no new results and suggests more research is needed to validate these options.
10 citations
,
January 2008 in “Biological and Pharmaceutical Bulletin” This study found that trans-3,4'-Dimethyl-3-hydroxyflavanone reduces active TGF-beta2 levels in human keratinocytes, suggesting it may enhance hair growth by suppressing the TGF-beta2 activation pathway.
August 2025 in “International Journal of Advanced Research in Science Communication and Technology” This study found that hybrid hair serums combining natural and synthetic ingredients may significantly enhance hair growth, density, and texture, highlighting their potential benefits for improving hair health and appearance.
January 2024 in “International Research Journal of Modernization in Engineering Technology and Science” This review suggests that combining nanotechnology with herbal components in hair cosmetics may improve the delivery and effectiveness of treatments for issues like damage, dandruff, and hair loss.
13 citations
,
September 2016 in “Cosmetics” This review discusses the components and effects of various hair cosmetic procedures and explores new techniques like camouflage methods and tattoo scalp, without reporting new clinical results.
2 citations
,
February 2016 in “Journal of sol-gel science and technology” This study found that 3-aminopropyltriethoxysilane penetrates hair fibers and improves the mechanical resistance of dry hair, addressing the needs for increased body in fine hair.
June 2026 in “Discover Nano” This review discusses current treatment strategies for alopecia and highlights the potential of lipid-based nanoparticles to improve drug delivery to the scalp and hair follicles, noting their ability to enhance skin penetration and drug stability while outlining associated challenges and the need for further research.
January 2026 in “International Journal of Health Engineering and Technology” In this study, researchers evaluated the effects of green spinach leaf extract on hair growth in New Zealand rabbits and found that the 15% concentration formula resulted in the highest average hair growth compared to other concentrations and controls.
59 citations
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May 2014 in “Expert Opinion on Therapeutic Targets” This review discusses current therapeutic targets and treatments for androgenic alopecia but reports no clinical results; the authors highlight the challenge of developing multi-target drugs for effective treatment.
42 citations
,
January 2017 in “Stem cells international” This study found that while extracellular matrix components like hyaluronic acid promoted larger organoid formation, other matrix components hindered hair follicle germ assembly in an in vitro model.