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In this study using a virtual screening approach, eriocitrin and silymarin were identified as potent flavonoid compounds that strongly and stably interacted with 5α-reductase type II, suggesting potential development as novel treatments for androgenic alopecia.

This review highlights various plant-based and herbal treatments that reportedly help prevent hair loss and encourage hair growth. It also explores the molecular mechanisms, identified plant compounds, recent technologies such as nanoarchitectonics, and patents related to hair growth promotion.

This review highlights the potential of plant-derived natural compounds as biocompatible and biodegradable materials in dermal and transdermal delivery systems, emphasizing their unexplored benefits and detailing recent advances in isolation techniques and drug delivery technologies.

This study found that isoliensinine, a natural compound identified from a database, effectively prevented stress-induced hair greying in mice by blocking β-2 adrenergic receptors on melanocyte stem cells in hair follicles.

This study found that the lignan compound VB-1 may promote hair follicle growth by enhancing Wnt/β-catenin signaling and increasing dermal papilla cell proliferation in vitro.

In this study, HPH-15, a newly synthesized compound, demonstrated potential in reducing skin fibrosis in a mouse model by targeting underlying pathogenic mechanisms and exhibited a good safety profile, warranting further clinical trials for fibrotic skin disorders like systemic sclerosis.

This review explores the extraction, characterization, and skin cosmetic effects of phenolic compounds and pigments from marine macroalgae, highlighting their documented benefits for skin health, such as whitening, moisturizing, photoprotection, and anti-aging effects, without adverse health impacts.

The fermented mixture may help hair growth and has antioxidative benefits.

In this in vitro study, Yifa Compound Prescription was reported to enhance human hair follicle growth and increase VEGF mRNA expression compared to blank serum.

In this study, Yifa compound treatment significantly improved female pattern hair loss and reduced sera DHT and DHEA levels after six months.

This systematic review highlights the potential of herbal shampoos, formulated with ingredients like Neem, Bhringraj, and Aloe Vera, to promote hair growth and reduce dandruff, while also discussing modern techniques and challenges in their development and evaluation.

This review discusses the traditional uses and biological activities of Aristotelia chilensis, summarizing its phytochemical composition and various potential health benefits, but reports no original research findings and highlights the need for further studies.

In this study, 33% of mice treated with polyphenol extract from green tea showed significant hair regrowth, while no control group mice exhibited hair growth.

This study found that none of the depigmenting compounds tested in beef heifers produced a permanent depigmenting effect, though visible depigmentation lasted up to 3 months.

This review discusses medical therapies for benign prostatic hyperplasia, highlighting the importance of personalizing treatments to individual patient needs and preferences.

This study found that a subfraction from Sansevieria trifasciata showed higher hair growth activity than other fractions in tests on rabbits.

This study found that 1,2,3,4-tetrahydroquinoline derivatives, particularly N-methyl-7-amino-1,2,3,4-tetrahydroquinoline, may be excellent blue dye candidates for human hair, offering superior color purity, stability, and fastness compared to 2,3-dihydroindoles.

This report examines the mechanisms by which TCDD affects human epidermal and carcinoma cells, aiming to create a risk assessment model for halogenated aromatic compounds, but presents no new clinical results.

This review discusses the bioactive substances found in native Korean Pinus densiflora and koraiensis and highlights the need for more research on their industrial application, despite known physiological effects.

This review discusses the dual role of selenium in human health, highlighting both the dangers of deficiency and potential toxicity from over-supplementation, without presenting new clinical results.

This review discusses the toxic effects and mechanisms of platinum compounds in cancer treatment, emphasizing the need for new compounds with different mechanisms of action; it reports no new clinical results.

This review discusses the potential of vitamins, minerals, and functional foods to promote hair growth and address hair loss, but reports no new clinical results.

This source reports that in adults with non-scarring alopecia, polyphenolic interventions significantly improved hair density and total area hair count compared to controls, although considerable variability was present in results, highlighting the need for further research.

This systematic review and meta-analysis found that polyphenolic interventions significantly improved hair density and total area hair count in adults with non-scarring alopecia, but substantial heterogeneity was observed.

This study evaluated the efficacy of polyphenolic compounds for hair growth in adults with non-scarring alopecia and found that these interventions significantly improved hair density and total area hair count compared to controls, although results were not significantly different from minoxidil.

This study reviewed in vivo studies and clinical trials on phenolic compounds, like tannins and flavonoids, for treating hair loss, noting their antioxidant and anti-inflammatory effects but highlighting the need for more clinical trials to confirm benefits.

This study found that Equisetum arvense, or horsetail, water extracts prepared with polyethylene glycol in an ultrasonic bath yielded the highest levels of phenolic compounds, such as hydroxycinnamic acids and flavonoids, indicating that this method improves the release of biologically active substances.

This review highlights the potential of herbal remedies like Aloe vera and Tea Tree Oil in managing acne, underscoring the need for cautious integration with conventional treatments due to limited large-scale clinical studies and variability in formulations.

This study found that Acanthus ebracteatus extract may promote the proliferation of human hair follicle dermal papilla cells and reported that its microemulsion was stable for 12 weeks.

In this computational study, the researchers observed that compounds in rosemary extract showed promising interactions with proteins involved in androgenic alopecia, suggesting potential for hair growth promotion and hair loss prevention, warranting further in vitro and in vivo validation.