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      Updated Treatment for Acne: Targeted Therapy Based on Pathogenesis

      research Updated Treatment for Acne: Targeted Therapy Based on Pathogenesis

      78 citations , June 2021 in “Dermatology and Therapy”
      This study highlights the evolving understanding of acne's pathophysiology and suggests that targeting pro-inflammatory cytokines such as IL-1β, IL-17, IL-23, and TNFα with biological antibodies may offer new treatment strategies for severe acne and its scars.
      Acne

      research Acne

      2 citations , May 2011 in “Harper's Textbook of Pediatric Dermatology”
      Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

      research A Comprehensive Review: The Bidirectional Role of Sebum in Skin Health

      December 2025 in “Bioengineering”
      This review explains that dysregulated sebum secretion and composition contribute to acne and impaired skin barriers while highlighting factors like diet and hormones affecting sebaceous activity, and identifies novel molecular targets and model systems for future therapeutic developments.
      The Role of Sex Hormones in Skin Health

      research The Role of Sex Hormones in Skin Health

      January 2025 in “Medical Research Archives”
      This review discusses the crucial role of sex hormones in maintaining and influencing skin health, suggesting ongoing research into hormonal treatments for skin conditions due to life stage changes.
      The Role of Linoleic Acid in Skin and Hair Health: A Review

      research The Role of Linoleic Acid in Skin and Hair Health: A Review

      December 2024 in “International Journal of Molecular Sciences”
      This review suggests that linoleic acid, an essential fatty acid, may have various beneficial effects on skin health and hair growth through diverse biological activities observed in animal or skin cell models.
      Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne

      research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne

      65 citations , February 2009 in “˜The œjournal of investigative dermatology/Journal of investigative dermatology”
      This paper discusses the hypothesis that anti-acne agents may work by reducing FGFR2 signaling, and emphasizes FGFR2's potential role in acne pathogenesis, but it reports no new experimental findings.
      Acne Vulgaris

      research Acne Vulgaris

      March 2017 in “InTech eBooks”
      This source provides a comprehensive review of acne vulgaris, highlighting its pathophysiology, epidemiology, molecular mechanisms, and treatment options, emphasizing the significance of addressing acne's psychosocial burden for adolescents and beyond.
      Acne and Systemic Disease

      research Acne and Systemic Disease

      76 citations , November 2009 in “Medical Clinics of North America”
      This article reviews the hormonal and medication-related factors associated with acne development but does not present new research findings.
      Treatment of Hyperandrogenism in Polycystic Ovary Syndrome

      research Treatment of hyperandrogenism in polycystic ovary syndrome

      1 citations , October 2010 in “Cambridge University Press eBooks”
      This review discusses strategies for managing dermatological symptoms of hyperandrogenism in PCOS by reducing androgen levels and actions, and reports no new clinical results.
      Exploring the Potential of Minoxidil Tretinoin Liposomal-Based Hydrogel for Topical Delivery in the Treatment of Androgenic Alopecia

      research Exploring the potential of minoxidil tretinoin liposomal based hydrogel for topical delivery in the treatment of androgenic alopecia

      15 citations , November 2019 in “Cutaneous and Ocular Toxicology”
      This study investigated a liposomal hydrogel system for delivering minoxidil and tretinoin to treat androgenic alopecia, finding that the system enhanced skin permeation of minoxidil while retaining tretinoin on the skin and was non-irritating in animal tests, suggesting its potential effectiveness.
      EEMCO Guidance for the In Vivo Assessment of Skin Greasiness

      research EEMCO Guidance for the in vivo Assessment of Skin Greasiness

      137 citations , January 2000 in “Skin Pharmacology and Physiology”
      This review outlines the factors affecting skin greasiness and sebum production, highlighting measurement challenges but reports no new clinical findings; further research may guide sebosuppressive treatments for acne.
      Medicinal Plants and Their Constituents in the Treatment of Acne Vulgaris

      research Medicinal Plants and their Constituents in the Treatment of Acne vulgaris

      15 citations , April 2022 in “Biointerface Research in Applied Chemistry”
      This review presents current evidence on medicinal plants and their phytoconstituents, such as phenolic compounds, used in acne treatment, highlighting their potential as alternatives to conventional therapies due to issues like antibiotic resistance and high cost.
      Cutaneous Adverse Effects of Targeted Therapies

      research Cutaneous adverse effects of targeted therapies

      192 citations , January 2015 in “Journal of the American Academy of Dermatology”
      This review discusses skin-related toxicities associated with targeted cancer therapies and emphasizes the need for dermatologists to understand and manage these adverse effects, but reports no new experimental results.
      Common Topical Medications

      research Common Topical Medications

      October 2018 in “Springer eBooks”
      The document concludes that various topical medications are effective for skin conditions but often cause skin irritation as a side effect.
      Side Effects of Common Acne Treatments

      research Side effects of common acne treatments

      38 citations , November 2012 in “Expert Opinion on Drug Safety”
      This article reviews different acne treatments and emphasizes the importance of being aware of their potential side effects, but reports no new clinical results.
      Oral Contraceptives as Anti-Androgenic Treatment of Acne

      research Oral Contraceptives as Anti-Androgenic Treatment of Acne

      16 citations , July 2002 in “JOGC/Journal of obstetrics and gynaecology Canada”
      This review discusses treatments for female acne, highlighting the effectiveness of low-dose oral contraceptives and noting their similar side effects to placebo; it reports no new clinical results.
      Current Concepts in the Pathogenesis and Treatment of Acne

      research Current concepts in the pathogenesis and treatment of acne

      8 citations , May 1998 in “Journal of Oral and Maxillofacial Surgery”
      This article discusses the importance of oral and maxillofacial surgeons understanding the pathogenesis and treatment of acne vulgaris, but it presents no new research findings.
      Recent Therapeutic Developments for Acne

      research Recent therapeutic developments for acne

      5 citations , February 2013 in “Expert Review of Dermatology”
      New acne treatments include combination creams, advanced retinoids, and light therapies, focusing on safety and patient adherence.