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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Photothermal hydrogels are promising for infection control and tissue repair, and combining them with other treatments could improve results and lower costs.

Stopping minoxidil treatment resumes balding; continuous use needed for results.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Some hair loss disorders are caused by genetic mutations affecting hair growth.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

New drug delivery methods can make natural compounds more effective and stable.

Apple extract called procyanidin B-2 was found to greatly increase hair growth.

The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.