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The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Created material boosts hair growth and kills bacteria for wound healing.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

People with hair loss, especially those with certain types, have lower zinc levels, and zinc supplements might help.

Iron deficiency common in women, not always linked to hair loss; more research needed.

Hair loss from Telogen Effluvium usually gets better within 6 months after addressing the cause.

New genes and pathways are important for testosterone production and male sexual development.

Certain groups may need vitamin supplements to improve hair health and prevent other health problems.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.