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This study found that two unrelated domestic shorthair cats had novel DSG4 gene mutations causing defective hair shafts, representing the first report of pathogenic DSG4 variants in domestic animals.

This case report describes a 73-year-old male with numerous colon polyps whose long-term use of Cape Aloe likely caused melanosis coli, which helped highlight the polyps' locations.

In patients undergoing treatment with capecitabine for colon cancer and metastatic breast cancer, this study observed that hand-foot syndrome occurred more frequently than with intravenous 5-FU, but other side effects were less common.

The researchers investigated a Maine Coon cat with suspected classical Ehlers-Danlos Syndrome and discovered a heterozygous deletion in the COL5A1 gene, underscoring the value of whole-genome sequencing for precise veterinary diagnostics.

This study found that keratin 7 protein expression increased in colon cancer epithelial-derived cells when treated with neutrophil and macrophage conditioned media, suggesting immune cell-derived factors may influence keratin expression.

This research observed that, in domestic cats like Maine Coon and Rex breeds, a "piebald" coat color pattern is likely influenced by the Silver locus, although the specific mutations involved are yet to be published.

In this study, gold nanoparticles-embedded ceria nanoparticles with enhanced antioxidant activities effectively reduced inflammation and colon injury in a colitis mouse model, suggesting their potential as a nano-therapeutic for inflammatory bowel disease.

This study found that ethanol and methanol extracts of Spirulina platensis did not exhibit cytotoxic activity on WiDr colon cancer cells.

This study demonstrates that collagen XVII is crucial for normal glomerular development, is present in normal colon epithelia, and plays a role in carcinogenesis in colorectal and squamous cell cancers.

This study found that the rs3185480 polymorphism in the APCDD1 gene was associated with an elevated risk of developing androgenic alopecia and reduced protein levels, potentially due to altered codon usage affecting translation efficiency.

This case report describes an unusual combination of hypertrichosis, androgenic alopecia, and trichomegaly in a patient with metastatic colon adenocarcinoma treated with cetuximab, with no adrenal or hormonal abnormalities detected.

This case report from BIRDEM General Hospital describes a 17-year-old girl with systemic lupus erythematosus who developed a rare form of lupus enteritis affecting her colon and rectum. Her symptoms improved significantly after treatment with corticosteroids and immunosuppressants.

This study found that in early retinal neurogenesis in mice, the transcription factor Lhx2 regulates Sonic Hedgehog signaling by controlling expression of pathway genes like the co-receptors Gas1 and Cdon.

This case report describes a 56-year-old male with chronic watery diarrhea, hyperpigmentation, and alopecia, in whom colonoscopy revealed multiple polypoidal lesions from the distal transverse colon to the rectum.

This abstract describes how triphala, a traditional Ayurvedic remedy composed of three fruits, is widely regarded as an effective and safe laxative and colon cleanser with potential cancer-fighting properties, supporting the body's strength and overall health without harming nutritional reserves.

This source reports that triphala, an Ayurvedic herbal preparation made from three fruits, is widely used as a safe and effective laxative and colon cleanser, with potential anti-cancer properties and additional health benefits like improving digestion and detoxifying the body.

This study identified a radio-resistant population of Krt15+ stem cells in the mouse small intestine that can initiate tumors, suggesting potential targets for colon cancer therapy.

This case report details a 71-year-old man diagnosed with Cronkhite-Canada Syndrome, highlighting the importance of early diagnosis and endoscopic evaluation due to the disease's progressive nature and significant mortality risk.

This study found that the restoration of CD103⁺γδ T cells in humans is associated with sustained remission in inflammatory bowel disease, suggesting a conserved role for these cells in limiting disease progression.

In this study, researchers developed a novel bio-patch from decellularized freeze-dried tumor tissues and hair melanin nanoparticles, which demonstrated enhanced wound healing in vivo by reducing oxidative stress, suppressing inflammation, and promoting angiogenesis.

This study found that high TSPEAR expression in colorectal cancer was associated with poor prognosis and correlated with various tumor and immune-related factors.

This study found that elevated TSPEAR expression in colorectal cancer was associated with poor overall prognosis and correlated with tumor infiltrating immune cells, suggesting its potential as a predictive biomarker.

In this study, researchers identified a unique Arg30stop mutation in the vitamin D receptor gene that causes hereditary vitamin D-resistant rickets in a young French-Canadian boy by truncating the receptor and causing hormone resistance.

This study identified KLHL24 as a new gene linked to a subtype of epidermolysis bullosa simplex, highlighting its role in unresolved cases by involving a degradation-resistant truncated protein impacting keratin turnover.

In this study, researchers identified a novel p.R50X mutation in the vitamin D receptor gene, linked to hereditary vitamin D-resistant rickets in two siblings.

The researchers reported finding a recessive nonsense variant in the EGFR gene responsible for perinatal lethality in the "Blonde d'Aquitaine" cattle breed, prompting the development of a screening test to help eradicate this genetic flaw.

This review discusses the anticancer properties of ginseng, including its potential to alleviate chemotherapy side effects, and calls for more research on its mechanisms of action in various cancers.

This study found that the evodiamine derivative 2-16 exhibited the highest antitumor activity and a broad spectrum of activity against various human cancer cell lines, with improved solubility.

This study found that ulcerative colitis is associated with diverse molecular changes and chronic inflammation, with some biomarker levels partially recovering during remission.

This case report highlights a rare instance of esophageal carcinoma in a patient with Cronkhite-Canada syndrome, emphasizing the importance of endoscopic surveillance for malignant gastrointestinal tumors in these patients.