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research TNC+ fibroblasts involve in skin inflammation via neuro-immune and interacting with T cells
This study found that TNC + fibroblasts are crucial in neuro-immune interactions in various skin diseases, particularly inflammation and tumors, by engaging extensively with immune cells and overexpressing inflammatory genes, suggesting their significant role in skin abnormalities.
research KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man
research Patient-convenient Long-term Alopecia Treatment via PLGA Microsphere-Loaded Candlelit Microneedle
This abstract discusses androgenetic alopecia treatments like oral finasteride and topical minoxidil, reporting limited treatment efficacy and no new findings, and emphasizes the psychological impact on patients.
research Cryogen Cooling Device for Anesthesia, Platelet-Rich Plasma Therapy, and Hair Loss
This abstract pertains to a dermatology-related academic profile without reporting any specific study findings. Results or research details are not provided.
research Chemotherapy-induced alopecia
This review discusses current knowledge and management strategies for chemotherapy-induced alopecia, highlighting the need for better research prioritization and providing patient support materials, but reports no new clinical results.
research NANOSTRUCTURE LIPID CARRIER TECHNOLOGY IN DRUG DELIVERY: ROUTE OF ADMINISTRATION, PREPARATION METHOD, CHARACTERIZATION, AND APPLICATION FOR ANTI-AGING
This review summarizes the potential of nanostructured lipid carriers in drug delivery systems, highlighting their promise in enhancing the stability and skin penetration of anti-aging cosmetics.
research Patient-Reported Outcomes From Phase III Neoadjuvant Systemic Trial Comparing Neoadjuvant Chemotherapy With Neoadjuvant Endocrine Therapy in Pre-Menopausal Patients With Estrogen Receptor-Positive and HER2-Negative, Lymph Node-Positive Breast Cancer
This study found that patient-reported outcomes were similar between neoadjuvant endocrine therapy and chemotherapy in premenopausal breast cancer patients, but future perspective was significantly better with endocrine therapy.
research Virgin Coconut And Fish Oil (VCFO) for Treatment of Fungal Cat Infection In Malang
This community service event in Malang, Indonesia, reported positive responses to using virgin coconut oil and fish oil as supportive therapy for treating fungal infections in cats, promoting hair regeneration, and educating pet owners.
research Hyperandrogenism in polycystic ovary syndrome and adrenal hyperplasia: finding differences to make a specific diagnosis
In this review, the authors aim to improve the differential diagnosis between hyperandrogenic PCOS and NCAH, which could lead to more personalized treatment strategies for patients experiencing hyperandrogenism.
research Assistants' CornerAssistants' Program for the 7th Annual Meeting of the International Society of Hair Restoration SurgeryStaffing: Continued responses to the article, “Staffing the Way I Like It,” Carlos Puig, DO (Forum, Vol. 9, No. 4, July/August 1999)Hydrogen Peroxide Revisited
This piece reflects on the past year of editing the Assistants' Corner and presents no new research findings.
research Hair Disorders Associated with Anticancer Agents
This review discusses types and prevention measures for chemotherapy-induced hair loss, highlighting scalp cooling as the most extensively used method to help prevent this condition, and reports no new clinical results.
research Effect of Nymphaea caerulea Flower Extract on Improving Scalp Diseases
This study found that Nymphaea caerulea flower extract may improve scalp condition by reducing sebum production, inhibiting inflammation and microbial factors, and decreasing cortisol and vascular permeability.
research Clinical observation of simultaneous continuous infusion of fluorouracil and disodium folinate combined with oxaliplatin for metastatic colorectal cancer
This study found that for metastatic colorectal cancer patients, substituting calcium folinate with disodium folinate in combination with fluorouracil and oxaliplatin showed similar effectiveness and safety as the mFOLFOX6 regimen.
research FOXN1 Is Critical for Onycholemmal Terminal Differentiation in Nude (Foxn1nu) Mice
This study found that mutations in the Foxn1 gene in nude mice affect not only hair but also nail structure and differentiation, offering insights into nail hypergranulosis pathogenesis relevant to human nail diseases.
research Cold Atmospheric Plasma for Breast Cancer
This review discusses the potential of cold atmospheric plasma as a selective antitumor therapy for breast cancer but reports no clinical results, emphasizing its promise and the challenges to its use in precision oncology.
research Chemotherapy‐induced alopecia: an exploratory questionnaire‐based study from Israel comparing knowledge, attitudes, and management practices among dermatologists and oncologists
This study highlights the need for targeted educational programs and better collaboration between dermatologists and oncologists to address knowledge gaps and improve patient care.
research Transarterial chemoembolization (TACE) combined with donafenib as first-line therapy for unresectable hepatocellular carcinoma (uHCC): A real-world clinical study.
In this retrospective study, combining TACE with Donafenib showed promising results as a first-line treatment for Chinese patients with unresectable hepatocellular carcinoma, yielding a median progression-free survival of 12.8 months and a one-year overall survival rate of 87.5%, along with a favorable safety profile.
research Expanding the Nude SCID/CID Phenotype Associated with FOXN1 Homozygous, Compound Heterozygous, or Heterozygous Mutations
This study describes various clinical phenotypes associated with FOXN1 mutations, finding that affected individuals may develop different severities of immunodeficiency based on their genetic mutations.
research Detection of mutations in the CYP21A2 gene: genotype-phenotype correlation in Slovenian couples with conceiving problems
This study found no significant difference in the prevalence of CYP21A2 mutations between couples with unexplained fertility problems and healthy controls, but identified an association between the c.290-13A/C>G mutation and clinical issues like hormone deviations and polycystic ovary syndrome.
research Performing a Nonsurgical Hair Restoration Consultation
This article aims to guide aesthetic practitioners on conducting thorough nonsurgical hair restoration consultations by understanding hair growth cycles and the causes of hair loss, including those from specific medications and conditions like Long COVID.
research Pharmacological Profile of 9,11-Dehydrocortexolone 17α-Butyrate (CB-03-04), a New Androgen Antagonist with Antigonadotropic Activity
This study found that the compound 9,11-dehydrocortexolone 17alpha-butyrate (CB-03-04) showed strong local antiandrogenic activity in animal models, suggesting potential for treating prostate conditions.
research TICE salvage chemotherapy treats germ-cell tumors effectively
TICE salvage chemotherapy is effective for treating germ-cell tumors with poor prognosis.
research Using disease symptomatology to guide treatment in patients with central centrifugal cicatricial alopecia: introduction of C-CAT scoring tool
This study introduced the C-CAT, a new assessment tool for central centrifugal cicatricial alopecia, and found that established treatments improved symptoms in most patients over six months.
research Exploring the Mechanism of Platycladi Cacumen in Intervening Androgenetic Alopecia Based on Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation
This study investigated the mechanisms of Platycladi Cacumen in treating androgenetic alopecia, identifying potential key components and targets but found no specific targets or regulatory mechanisms.
research Cisd2 deficiency impairs neutrophil function by regulating calcium homeostasis via Calnexin and SERCA
This study used Cisd2 knockout mice models and found that these mice display premature aging characteristics and an increase in dysfunctional neutrophils, suggesting Cisd2's role in calcium homeostasis and neutrophil function via interactions with Calnexin and SERCA.
research Hydrogel Microneedles Loaded With a Reactive Oxygen Species (ROS)‐Responsive Carbon Monoxide Donor and Finasteride for Synergistic Treatment of Androgenetic Alopecia
In a mouse model study, researchers developed a methacrylated hyaluronic acid-based hydrogel microneedle patch co-loaded with finasteride and a carbon monoxide-releasing molecule for androgenetic alopecia, which showed better hair regrowth and safety compared to traditional treatments, offering an innovative approach with minimized systemic side effects.
research Comprehensive treatment of Cronkhite-Canada syndrome: A case report and literature review
This review discusses the potential of traditional Chinese medicine to relieve clinical symptoms in cases of CCS and emphasizes the need for further large-scale, long-term studies to verify these effects.
research Effects of cepharanthin and minoxidil on growth and differentiation of the cultured hair and hair follicle cells; An electron microscopic analysis
research Trichorrhexis nodosa improving with oral minoxidil: a case report
Oral minoxidil may help improve fragile hair.