research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
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30-60 / 289 results research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
research Expression Profile Analysis of MicroRNAs During Hair Follicle Development in the Sheep Fetus
Ten miRNAs may play key roles in starting secondary hair follicle development in sheep foetuses.
research The Peach RGF/GLV Signaling Peptide pCTG134 Is Involved in a Regulatory Circuit That Sustains Auxin and Ethylene Actions
The peach gene CTG134 helps control the interaction between auxin and ethylene, which could lead to new agricultural chemicals.
research Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity
A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
research Expression of Steroidogenic Enzymes in Human Sebaceous Glands
Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
research Alopecia in Harlequin Mutant Mice Is Associated with Reduced AIF Protein Levels and Expression of Retroviral Elements
Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.
research Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN
The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
research The ZIP7 Gene (Slc39a7) Encodes a Zinc Transporter Involved in Zinc Homeostasis of the Golgi Apparatus
The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.
research Fibroblasts: Origins, Definitions, and Functions in Health and Disease
Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
research Scalp Sebaceous Physiology
The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.
research New Intranasal and Injectable Gene Therapy for Healthy Life Extension
Gene therapy in mice increased lifespan and improved health without causing cancer.
research Gender Differences in Skin: A Review of the Literature
Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.
research Interferons in Dermatology
Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.
research Expression Patterns of Three Estrogen Receptor Genes During Zebrafish Development: Evidence for High Expression in Neuromasts
The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.
research HtrA1L364P Leads to Cognitive Dysfunction and Vascular Destruction Through TGF-β/Smad Signaling Pathway in CARASIL Model Mice
The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.
research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.
research Phospholipase A2 Is Required for PIN-FORMED Protein Trafficking to the Plasma Membrane in the Arabidopsis Root
Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.
research Enhanced Restoration of In Situ-Damaged Hairs by Intradermal Transplantation of Trichogenous Dermal Cells
Transplanting a mix of specific skin cells can significantly improve the repair of damaged hair follicles.
research Bioinformatics Analysis of Genes Associated with Patchy-Type Alopecia Areata: CD2 May Be a New Therapeutic Target
CD2 might be a new treatment target for patchy alopecia areata.
research TOR Tour to Auxin
The plant hormone auxin activates the TOR pathway, affecting gene expression related to growth and cell size.
research Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors
New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
research Resveratrol Derivatives: A Patent Review (2009–2012)
New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
research Expression and Roles of Steroidogenic Acute Regulatory (StAR) Protein in Non-Classical, Extra-Adrenal, and Extra-Gonadal Cells and Tissues
The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
research Functional Enhancers as Master Regulators of Tissue-Specific Gene Regulation and Cancer Development
Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.
research Vitamin D Receptor: New Assignments for an Already Busy Receptor
The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.
research Human and Animal Cells Under Influence of Different Lighting and Stimuli
Different light affects cell functions and can help treat skin conditions.
research Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.
research Androgenetic Alopecia: Role of the Phototrichogram
Phototrichogram helps assess hair loss severity.