179 citations
,
July 2016 in “Nature Reviews Molecular Cell Biology” This review examines how epigenetic dysregulation affects adult stem cell function, noting that impacts range from minor to serious disruptions in tissue homeostasis and potential cancer development.
170 citations
,
December 2009 in “Histopathology” This review discusses the histopathological diagnosis of scarring and non-scarring alopecias, emphasizing the importance of adequate tissue sampling and clinical information; it reports no new empirical results.
163 citations
,
April 1953 in “Acta radiologica” Radiation therapy with a higher dose for the brain improves survival in cerebellar medulloblastoma.
158 citations
,
January 2015 in “Artificial Intelligence in Medicine” This study found that DrugNet, a network-based prioritization method, effectively improves drug repositioning tasks, achieving high performance in validation tests and clinical trial comparisons.
149 citations
,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” This article provides contact information for Bruce A. Morgan and features no new research findings.
141 citations
,
August 2018 in “Nature Reviews Microbiology” This review discusses the molecular mechanisms by which oncogenic viruses contribute to cancer development through manipulation of host cellular functions and highlights the need for further research into virus-associated cancers, reporting no new results.
131 citations
,
September 2010 in “The Laryngoscope” This study found that forehead feminization significantly contributes to recognizing female gender and reported that feminizing forehead cranioplasty is a safe procedure with a low complication rate.
100 citations
,
July 2004 in “The Journal of Sexual Medicine” This article reviews how various hormones may affect female sexual function and provides recommendations for diagnosing and treating endocrinologic sexual difficulties, but it reports no new clinical results.
98 citations
,
October 2012 in “Dermatologic Clinics” This article reviews the impact of nutritional deficiencies on hair health, detailing how they can cause structural abnormalities, pigmentation changes, or hair loss; it presents no new clinical findings.
87 citations
,
July 2018 in “Nursing Clinics of North America” This review discusses the diagnostic criteria and treatment options for polycystic ovary syndrome focusing on metabolic subtypes and reports no clinical results.
86 citations
,
May 2013 in “American journal of obstetrics and gynecology” This article reviews the care of transgender patients, encompassing diagnosis, treatment options, and challenges in health care access, but does not present new research findings; the authors emphasize the critical role of providers in addressing transgender health needs.
74 citations
,
June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that hair follicles are a significant and efficient pathway for the absorption of topical minoxidil foam in humans, with faster blood detection when follicles are open.
69 citations
,
April 2010 in “Dermatologic Surgery” This review discusses the safety and efficacy of bimatoprost ophthalmic solution 0.03% for enhancing eyelash growth by influencing the eyelash hair cycle and follicles, and it reports no new results.
67 citations
,
April 2007 in “Journal der Deutschen Dermatologischen Gesellschaft” This article reviews the development and formulation of shampoos, emphasizing their dual role as cosmetic and medicinal products, but presents no new experimental findings.
62 citations
,
July 2018 in “Lasers in Medical Science” In this review, the researchers highlight LED therapy as an emerging and safe treatment for skin inflammatory conditions, aging, and hair growth disorders, noting its integration into dermatological practice but emphasizing the need for more controlled studies to confirm its efficacy.
60 citations
,
January 2023 in “Biogerontology” This review examines testosterone's role in male health and aging but reports no new clinical results; the authors highlight the need for further research on optimal testosterone levels to prevent age-related conditions.
58 citations
,
March 2013 in “Human Reproduction Update” This review discusses various substances that can impact male fertility and stresses that products should be confirmed 'sperm-safe' through rigorous testing, not assumptions; it reports no new study results.
58 citations
,
January 2003 in “Biological & Pharmaceutical Bulletin” This study identified novel compounds from Bombax ceiba stem bark, including shamimicin, with potent hypotensive effects, and reported that a specific fraction had adverse effects on heart, liver, and kidneys in mice.
54 citations
,
September 2000 in “Archives of dermatology” In this study, 95% of respondents reported severe hair breakage or loss after using the Rio Hair Naturalizer System, with many experiencing significant and lasting hair loss.
53 citations
,
May 2001 in “The American journal of the medical sciences” This article reviews common skin eruptions in chemotherapy patients and discusses how recognizing these patterns can help avoid unnecessary changes to cancer treatment; it reports no new clinical results.
48 citations
,
September 2013 in “Oncologist” This study reported that alopecia is a common but often underreported side effect of endocrine-based cancer therapies, with tamoxifen showing the highest incidence of hair loss among analyzed treatments.
46 citations
,
May 2009 in “Maturitas” This study found that taking a daily oral dose of 50mg DHEA for one year had no significant impact on blood lipids, insulin sensitivity, or the endometrium in postmenopausal women with low libido.
45 citations
,
August 2010 in “Hormone Molecular Biology and Clinical Investigation” This study found that SRD5a-3 is a highly efficient enzyme for converting hormones into androgens, with dutasteride being a much more potent inhibitor of SRD5a-3 than SRD5a-2.
45 citations
,
August 1994 in “Journal of Chromatography B: Biomedical Sciences and Applications” Method detects finasteride in plasma and semen with high sensitivity and accuracy.
43 citations
,
November 2019 in “PLoS ONE” This study revealed that differential gene and protein expression in the "Yufen I" H line chicken breed is crucial for Columbian plumage coloration, particularly in the melanogenesis pathway.
43 citations
,
July 2016 in “European journal of pharmaceutical sciences” This study found that dexamethasone-loaded Eudragit® L 100 nanoparticles displayed controlled drug release depending on pH levels, with minimal toxicity to human fibroblasts.
43 citations
,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” This review examines the histopathologic features of four common types of noncicatricial alopecia and reports no new clinical results.
41 citations
,
December 2016 in “International Journal of Women's Dermatology” This review discusses the unique dermatologic needs of transgender individuals during transitioning and emphasizes the importance of accommodating care in medical settings; it reports no new clinical results.
40 citations
,
May 2012 in “British Journal of Dermatology” This study reviewed scalp biopsies from African-American patients, identifying distinct features and diagnostic clues for scarring alopecia types such as traction alopecia and central centrifugal cicatricial alopecia.
40 citations
,
December 2011 in “British Journal of Dermatology” This article reviews how chronological aging affects female scalp hair growth and suggests that multiple factors, including environmental influences, contribute to female pattern hair loss; no new clinical results are presented.