133 citations
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July 2020 in “Cells” This review discusses the modern approach of skin tissue engineering for chronic wound treatment, focusing on bioengineered artificial skin substitutes and assessing innovations in biomaterials and cell use; it reports no new clinical results.
83 citations
,
November 2002 in “British Journal of Dermatology” This study found no direct relationship between low serum ferritin and chronic diffuse telogen hair loss in women, questioning the usefulness of serum ferritin measurement and iron supplementation for managing this condition.
45 citations
,
January 1999 in “Dermatology” This study validated the VQ-Dermato, the first dermatology-specific quality of life instrument in French, and found it to be reliable, acceptable for routine use, and more responsive than the SF36.
19 citations
,
January 2017 in “Stem Cells International” This review discusses the potential of adipose-derived stem cells for treating vitiligo, hair loss, and chronic wound healing, but reports no new clinical results and suggests the need for further investigation.
17 citations
,
January 1993 in “Dermatology” This report describes two cases of chronic arsenicism, one involving criminal poisoning by a sibling and the other associated with prolonged use of Fowler's solution.
6 citations
,
July 2022 in “Journal of health economics and outcomes research” This study found that US adolescents with alopecia areata, especially those with alopecia totalis or universalis, experience significantly higher healthcare costs and resource use compared to matched controls.
December 2024 in “Ukrainian Journal of Dermatology Venerology Cosmetology” This study observed that after 12 weeks of using the nutraceutical Alpenta, women with acute or chronic telogen effluvium experienced significant improvements in hair growth parameters, including increased anagen hair percentage, hair density, and diameter, with high patient satisfaction and good product tolerability reported.
December 2023 in “Tuberkuloz ve Toraks/Tüberküloz ve toraks” This study identified female sex and specific radiological findings as risk factors for chronic post-COVID syndrome, while long-term use of angiotensin-2 receptor blockers was linked to fewer chronic symptoms.
December 2023 in “Alzheimer's & dementia” In this rodent study, researchers found that the drug finasteride may reduce anxiety and depression-like behaviors in a model of aging, despite inducing metabolic disturbances and depressive-like behaviors in young rats, suggesting potential considerations for its use in elderly populations.
January 2020 in “Acta Scientiae Veterinariae” In this case report, a combination of ozone therapy, low-level laser, and herbal medicine gel effectively improved healing in a dog with chronic bite wounds.
January 2007 in “UNIFESP Institutional Repository (Universidade Federal de São Paulo)” This study found that patients with chronic migraine who excessively use symptomatic medications had a higher prevalence of anxiety and mood disorders, suggesting these psychiatric diagnoses may influence medication overuse.
August 2006 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A simple wash test can help differentiate between two types of hair loss, and dermatoscopy should be used for further clarification.
25 citations
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May 2012 in “Journal of The European Academy of Dermatology and Venereology” In this study, 62.1% of Korean patients with chronic dermatologic diseases reported using complementary and alternative medicine, though many were dissatisfied with the results.
23 citations
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January 2007 in “Archives of Andrology” This study reported that semen quality improved in three young men after discontinuing long-term finasteride use, although meiotic abnormalities persisted.
May 2025 in “European Journal of Case Reports in Internal Medicine” In this case report, an 81-year-old male with chronic kidney disease developed cardiac tamponade while on minoxidil for hypertension, highlighting the rare but serious risk of pericardial effusion from this medication and emphasizing the need for vigilant monitoring, especially in vulnerable patients.
May 2021 in “Journal of the Endocrine Society” This case study highlights the overlooked condition of opioid-induced adrenal insufficiency, emphasizing the need for increased clinician awareness of its potential prevalence in chronic opioid users.
19 citations
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August 2010 in “Journal der Deutschen Dermatologischen Gesellschaft” This review discusses plant extracts for dermatological use, highlighting evidence that some can reduce edema in chronic venous insufficiency or help treat actinic keratoses, but it reports no new clinical results.
2 citations
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January 2021 in “Cureus” This case study describes a three-year-old girl who developed acute hepatitis and pancytopenia, potentially due to chronic use of Senna, highlighting possible liver and bone marrow toxicity.
February 2026 in “Molecules” This study developed a sensitive method for analyzing nine biomarkers in hair, revealing an association between chronic tobacco smoke exposure and stress, highlighting its potential use in understanding the relationship between long-term tobacco exposure and chronic stress.
April 2026 in “International Journal of Clinical Case Reports and Reviews” In this preclinical study, researchers developed and evaluated a new non-invasive laser system designed for personalized medical use, showing its potential for chronic disease management and adjunctive fat reduction by offering enhanced treatment precision and adaptability over existing devices.
7 citations
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November 2006 in “Journal of immunological methods” This study found that the novel dot-block method can effectively measure early- and advanced-glycation products in hair, suggesting its potential for monitoring diabetes progression and other chronic conditions.
December 2024 in “Pharmaceutics” This review systematically examined recent advancements in spironolactone-loaded nanocarriers, revealing that lipid and vesicular nanoparticles enhance bioavailability and skin penetration for treating androgen-dependent disorders, but highlighted the need for further clinical studies to optimize their use.
May 2023 in “Stem Cells International” In this study, researchers used single-cell RNA sequencing to identify cell types and molecular differences in subcutaneous adipose tissue from various anatomical sites, suggesting that certain subpopulations of human adipose stem cells might improve the treatment of chronic refractory wounds.
104 citations
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October 1999 in “The Journal of Urology” This study concluded that daily treatment with 1 mg finasteride did not affect spermatogenesis or semen production in young men and had small, reversible effects on prostate volume and serum PSA.
72 citations
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March 2023 in “Biomolecules” This study reviewed the use of dupilumab, beyond its approved indications for atopic dermatitis and prurigo nodularis, and found effective treatment reports for various chronic inflammatory skin diseases such as bullous autoimmune diseases, eczema, and alopecia areata, highlighting its broad potential in dermatology.
40 citations
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May 2010 in “Australasian Journal of Dermatology” This study suggests that chronic telogen effluvium may be due to a reduction in the variance of anagen duration, resulting in recurrent hair shedding with minimal long-term hair volume loss.
26 citations
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January 2017 in “Acta dermato-venereologica” This review examines the use of monoaminergic antidepressants for inflammatory skin disorders and reports they may reduce dermatological symptoms, suggesting a potential role beyond treating psychiatric conditions.
20 citations
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February 2004 in “Clinical & Experimental Immunology” This study suggests that long-term treatment with the contact sensitizer SADBE in mice may reduce leucocyte traffic in alopecia areata through impaired leucocyte extravasation.
14 citations
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September 1968 in “Archives of Dermatology” This study found that the use of hot combs with petrolatum in Black women causes irreversible alopecia limited to the crown of the scalp, resulting in follicular scarring.
13 citations
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July 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This article discusses the use of trichoscopy as a helpful tool for early diagnosis and monitoring of dissecting cellulitis, but it reports no new clinical results.