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The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.

Hairless HRS/J mice resist Bacillus anthracis skin infections due to high numbers of immune cells, not because they lack hair follicles.

A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.

A 3-year-old boy lost all his hair due to a rare reaction to phenobarbital, but it grew back after steroid treatment.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Doctors should consider SLE in males even if antinuclear antibody tests are negative.

Advanced imaging techniques are crucial for accurately diagnosing Monilethrix, a rare hair disorder.

There are many treatments for common hair loss, but more trials are needed to decide which are best.

Low-level laser therapy can significantly regrow hair in alopecia areata.

Two sisters have rare hair disorders causing short, fragile, kinky hair.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

COX-2 and Bcl-2 proteins are involved in Lichen Planus.

Neurohormones help control skin health and could treat skin disorders.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Reduced AR gene methylation may cause early pubic hair growth in girls.